SH3GLB2 Antibody - #DF4503

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Product: SH3GLB2 Antibody
Catalog: DF4503
Description: Rabbit polyclonal antibody to SH3GLB2
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 48 KD; 44kD(Calculated).
Uniprot: Q9NR46
RRID: AB_2836854

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(92%)
Clonality:
Polyclonal
Specificity:
SH3GLB2 Antibody detects endogenous levels of total SH3GLB2.
RRID:
AB_2836854
Cite Format: Affinity Biosciences Cat# DF4503, RRID:AB_2836854.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Endophilin B2; Endophilin-B2; OTTHUMP00000022320; PP6569; PP9455; Retinoid receptor induced gene 1; RRIG1; SH3 containing protein SH3GLB2; SH3 domain GRB2 like endophilin B2; SH3 domain-containing GRB2-like protein B2; SH3GLB2; SHLB2_HUMAN;

Immunogens

Immunogen:
Uniprot:

Q9NR46(SHLB2_HUMAN) >>Visit HPA database.

Gene(ID):
SH3GLB2(56904)
Expression:
Q9NR46 SHLB2_HUMAN:

Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.

Sequence:
MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
92
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NR46 As Substrate

Site PTM Type Enzyme
M1 Acetylation
K6 Methylation
K7 Methylation
K7 Ubiquitination
S10 Phosphorylation
K26 Ubiquitination
K32 Ubiquitination
K50 Ubiquitination
K55 Ubiquitination
Y77 Phosphorylation
K79 Ubiquitination
T108 Phosphorylation
T109 Phosphorylation
K117 Ubiquitination
K123 Ubiquitination
T142 Phosphorylation
K153 Ubiquitination
K173 Ubiquitination
K178 Acetylation
K180 Acetylation
K185 Acetylation
K185 Ubiquitination
T188 Phosphorylation
T195 Phosphorylation
R198 Methylation
S205 Phosphorylation
S207 Phosphorylation
R230 Methylation
S259 Phosphorylation
T262 Phosphorylation
Y263 Phosphorylation
K276 Ubiquitination
S395 Phosphorylation

Research Backgrounds

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.

Subunit Structure:

Homodimer, and heterodimer with SH3GLB1.

Family&Domains:

Belongs to the endophilin family.

Research Fields

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

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