RCL1 Antibody - #DF4444
| Product: | RCL1 Antibody |
| Catalog: | DF4444 |
| Description: | Rabbit polyclonal antibody to RCL1 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 41 KD; 41kD(Calculated). |
| Uniprot: | Q9Y2P8 |
| RRID: | AB_2836799 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4444, RRID:AB_2836799.
Fold/Unfold
RCL1; RNA 3' terminal phosphate cyclase like protein; RNA cyclase homolog; RNA terminal phosphate cyclase like 1; RNAC; RPC2; RPCL1; RTC2;
Immunogens
- Q9Y2P8 RCL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCPVRKVLKPIQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTSGTFLSAELASNPQGQGAAVLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLKSFFQIMFKIETKPCGEELKGGDKVLMTCVGIGFSNLSKTLK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y2P8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S26 | Phosphorylation | Uniprot | |
| T59 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| T71 | Phosphorylation | Uniprot | |
| Y74 | Phosphorylation | Uniprot | |
| Y75 | Phosphorylation | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| R118 | Methylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K141 | Ubiquitination | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| K178 | Ubiquitination | Uniprot | |
| T183 | Phosphorylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| R207 | Methylation | Uniprot | |
| Y224 | Phosphorylation | Uniprot | |
| S321 | Phosphorylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| K351 | Ubiquitination | Uniprot | |
| T359 | Phosphorylation | Uniprot | |
| S366 | Phosphorylation | Uniprot | |
| S369 | Phosphorylation | Uniprot |
Research Backgrounds
Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity).
Nucleus>Nucleolus.
Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
Research Fields
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
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