RAB6A Antibody - #DF4407
| Product: | RAB6A Antibody |
| Catalog: | DF4407 |
| Description: | Rabbit polyclonal antibody to RAB6A |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 24 KD; 24kD(Calculated). |
| Uniprot: | P20340 |
| RRID: | AB_2836762 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4407, RRID:AB_2836762.
Fold/Unfold
GTP binding protein RAB6A'; GTP binding protein RAB6B; Oncogene RAB6; Rab 6; Rab GTPase; Rab-6; RAB6; RAB6 member RAS oncogene family; RAB6A; RAB6A member RAS oncogene family; Rab6A variant 3; RAB6A'; RAB6A_HUMAN; RAB6B; Ras related protein Rab 6A; Ras-related protein Rab-6A; RCO4 3;
Immunogens
- P20340 RAB6A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P20340 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| T3 | Phosphorylation | Uniprot | |
| S23 | Phosphorylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| T54 | Phosphorylation | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| R60 | Methylation | Uniprot | |
| T61 | Phosphorylation | Uniprot | |
| T69 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| R112 | Methylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| K192 | Acetylation | Uniprot |
Research Backgrounds
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER.
Prenylated.
Golgi apparatus membrane>Lipid-anchor.
Note: BICD2 facilitates its targeting to Golgi apparatus membrane.
Golgi apparatus membrane>Lipid-anchor.
Golgi apparatus membrane>Lipid-anchor.
Ubiquitous.
Interacts with BICDL1; leads to its accumulation in the pericentrosomal region (By similarity). Interacts with SCYL1BP1. Interacts with VSP52 and RABGAP1. Interacts with GCC2 (via its GRIP domain). Interacts with RAB6IP1 (via its RUN 1 domain). Isoform 1 interacts with RAB6KIFL. Isoform 2 does not interact with RAB6KIFL. Isoform 1 interacts with BICD1. Isoform 2 interacts with BICD1. Isoform 1 interacts with BICD2. Isoform 2 interacts with BICD2. Interacts with TMF1. Isoform 1 (GTP-bound) interacts with DYNLRB1; the interaction is direct. Isoform 2 (GDP-bound) interacts with DYNLRB1; the interaction is direct. Interacts with PIFO. Interacts (GTP-bound) with APBA1/MINT1 isoform 2, also called Mint1_826, but not with isoform 1. Interacts with RIC1 and RGP1; the interactions are direct with a preference for RAB6A-GDP.
(Microbial infection) Interacts with human cytomegalovirus protein UL32.
Belongs to the small GTPase superfamily. Rab family.
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