IQGAP3 Antibody - #DF4389

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Product: IQGAP3 Antibody
Catalog: DF4389
Description: Rabbit polyclonal antibody to IQGAP3
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 180 KD; 185kD(Calculated).
Uniprot: Q86VI3
RRID: AB_2836744

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(91%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(91%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
IQGAP3 Antibody detects endogenous levels of total IQGAP3.
RRID:
AB_2836744
Cite Format: Affinity Biosciences Cat# DF4389, RRID:AB_2836744.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

IQ motif containing GTPase activating protein 3; IQGA3_HUMAN; IQGAP 3; IQGAP3; MGC10170; MGC10831; MGC1947; OTTHUMP00000031854; OTTHUMP00000031855; Ras GTPase activating like protein IQGAP3; Ras GTPase-activating-like protein IQGAP3;

Immunogens

Immunogen:
Uniprot:

Q86VI3(IQGA3_HUMAN) >>Visit HPA database.

Gene(ID):
IQGAP3(128239)
Sequence:
MERRAAGPGWAAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEACLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAHIGLPSTFFPETTDIYDKKNMPRVVYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELSNMASELAKYGLQLPAFSKIGGILANELSVDEAAVHAAVLAINEAVERGVVEDTLAALQNPSALLENLREPLAAVYQEMLAQAKMEKAANARNHDDRESQDIYDHYLTQAEIQGNINHVNVHGALEVVDDALERQSPEALLKALQDPALALRGVRRDFADWYLEQLNSDREQKAQELGLVELLEKEEVQAGVAAANTKGDQEQAMLHAVQRINKAIRRRVAADTVKELMCPEAQLPPVYPVASSMYQLELAVLQQQQGELGQEELFVAVEMLSAVVLINRALEARDASGFWSSLVNPATGLAEVEGENAQRYFDALLKLRQERGMGEDFLSWNDLQATVSQVNAQTQEETDRVLAVSLINEALDKGSPEKTLSALLLPAAGLDDVSLPVAPRYHLLLVAAKRQKAQVTGDPGAVLWLEEIRQGVVRANQDTNTAQRMALGVAAINQAIKEGKAAQTERVLRNPAVALRGVVPDCANGYQRALESAMAKKQRPADTAFWVQHDMKDGTAYYFHLQTFQGIWEQPPGCPLNTSHLTREEIQSAVTKVTAAYDRQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIYLEWLQYFKANLDAIIKIQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRRFAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIKIGLLVKNRITLQEVVSHCKKLTKRNKEQLSDMMVLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPIYLAKLIFQMPQNKTTKFMEAVIFSLYNYASSRREAYLLLQLFKTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDKVLSVHTDPVHLYKNWINQTEAQTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPEERFAVDEYSDMVAVAKPMVYITVGELVNTHRLLLEHQDCIAPDHQDPLHELLEDLGELPTIPDLIGESIAADGHTDLSKLEVSLTLTNKFEGLEADADDSNTRSLLLSTKQLLADIIQFHPGDTLKEILSLSASREQEAAHKQLMSRRQACTAQTPEPLRRHRSLTAHSLLPLAEKQRRVLRNLRRLEALGLVSARNGYQGLVDELAKDIRNQHRHRHRRKAELVKLQATLQGLSTKTTFYEEQGDYYSQYIRACLDHLAPDSKSSGKGKKQPSLHYTAAQLLEKGVLVEIEDLPASHFRNVIFDITPGDEAGKFEVNAKFLGVDMERFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLLIFLLNKKFLRK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Rabbit
100
Zebrafish
91
Chicken
91
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q86VI3 As Substrate

Site PTM Type Enzyme
Y13 Phosphorylation
K70 Ubiquitination
K83 Ubiquitination
Y140 Phosphorylation
K164 Ubiquitination
K166 Ubiquitination
T168 Phosphorylation
S201 Phosphorylation
K314 Ubiquitination
R324 Methylation
K345 Ubiquitination
K357 Ubiquitination
K386 Ubiquitination
K398 Methylation
K537 Ubiquitination
S539 Phosphorylation
K542 Ubiquitination
K573 Ubiquitination
K576 Ubiquitination
T628 Phosphorylation
K660 Ubiquitination
K876 Ubiquitination
K907 Ubiquitination
K938 Acetylation
K943 Ubiquitination
K947 Acetylation
K949 Acetylation
K981 Ubiquitination
K1011 Acetylation
K1011 Ubiquitination
T1012 Phosphorylation
K1019 Ubiquitination
K1021 Ubiquitination
K1067 Ubiquitination
K1080 Acetylation
K1080 Ubiquitination
Y1098 Phosphorylation
T1101 Phosphorylation
T1134 Phosphorylation
S1135 Phosphorylation
S1136 Phosphorylation
K1152 Ubiquitination
K1158 Ubiquitination
K1169 Ubiquitination
K1245 Ubiquitination
Y1268 Phosphorylation
S1269 Phosphorylation
T1289 Phosphorylation
S1360 Phosphorylation
T1362 Phosphorylation
K1370 Ubiquitination
K1402 Ubiquitination
T1412 Phosphorylation
T1415 Phosphorylation
S1424 Phosphorylation
T1426 Phosphorylation
S1429 Phosphorylation
K1436 Ubiquitination
S1509 Phosphorylation
S1523 Phosphorylation
K1524 Ubiquitination
S1525 Phosphorylation
S1526 Phosphorylation
K1531 Ubiquitination
Y1537 Phosphorylation
T1538 Phosphorylation
K1545 Ubiquitination

Research Backgrounds

Research Fields

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

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