RAPGEF5 Antibody - #DF4382
| Product: | RAPGEF5 Antibody |
| Catalog: | DF4382 |
| Description: | Rabbit polyclonal antibody to RAPGEF5 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 60 KD; 68kD(Calculated). |
| Uniprot: | Q92565 |
| RRID: | AB_2836737 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4382, RRID:AB_2836737.
Fold/Unfold
GFR; Guanine nucleotide exchange factor for Rap1; KIAA0277; M Ras regulated Rap GEF; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; MR GEF; MR-GEF; MRas-regulated guanine nucleotide exchange factor; MRGEF; Rap guanine nucleotide exchange factor (GEF) 5; Rap guanine nucleotide exchange factor 5; Rapgef5; Related to Epac; Repac; RPGF5_HUMAN;
Immunogens
- Q92565 RPGF5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSSRLRVFDPHLERKDSAAALSDRELPLPTFDVPYFKYIDEEDEDDEWSSRSQSSTEDDSVDSLLSDRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPRRKRKVLHLVSQWIALYKDWLPEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVTETEEIFCHVYITEHSYVSVKAKVSSIAQEILKVVAEKIQYAEEDLALVAITFSGEKHELQPNDLVISKSLEASGRIYVYRKDLADTLNPFAENEESQQRSMRILGMNTWDLALELMNFDWSLFNSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGDLSPKEHQELKSYVNHLYVIDSQQALFELSHRIEPRV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q92565 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y70 | Phosphorylation | Uniprot | |
| S74 | Phosphorylation | Uniprot | |
| T76 | Phosphorylation | Uniprot | |
| Y126 | Phosphorylation | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| K191 | Acetylation | Uniprot | |
| T207 | Phosphorylation | Uniprot | |
| Y211 | Phosphorylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| S225 | Phosphorylation | Uniprot | |
| S471 | Phosphorylation | Uniprot | |
| S555 | Phosphorylation | Uniprot | |
| S573 | Phosphorylation | Uniprot |
Research Backgrounds
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.
Nucleus.
Widely expressed with highest levels in brain.
Research Fields
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Rap1 signaling pathway. (View pathway)
Restrictive clause
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For Research Use Only.
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