Product: PPP1R16A Antibody
Catalog: DF4344
Description: Rabbit polyclonal antibody to PPP1R16A
Application: WB
Reactivity: Human, Rat
Mol.Wt.: 60~70kD; 58kD(Calculated).
Uniprot: Q96I34
RRID: AB_2836712

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
PPP1R16A Antibody detects endogenous levels of total PPP1R16A.
RRID:
AB_2836712
Cite Format: Affinity Biosciences Cat# DF4344, RRID:AB_2836712.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

2900084E10Rik; Likley ortholog of mouse myosin phosphatase targeting subunit 3; MGC14333; Myosin phosphatase target subunit 3; Myosin phosphatase targeting subunit 3; Myosin phosphatase-targeting subunit 3; MYPT3; PP16A_HUMAN; PPP1R16A; Protein phosphatase 1 regulatory subunit 16A; Protein phosphatase 1, regulatory (inhibitor) subunit 16A; R75527;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEAQGKKGPGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSLLRRRTSSAGSRGKVVRRVSLTQRTDLYRKQHAQEAIVWQQPPPTSPEPPEDNDDRQTGAELRPPPPEEDNPEVVRPHNGRVGGSPVRHLYSKRLDRSVSYQLSPLDSTTPHTLVHDKAHHTLADLKRQRAAAKLQRPPPEGPESPETAEPGLPGDTVTPQPDCGFRAGGDPPLLKLTAPAVEAPVERRPCCLLM

PTMs - Q96I34 As Substrate

Site PTM Type Enzyme
S18 Phosphorylation
S60 Phosphorylation
S199 Phosphorylation
S353 Phosphorylation
S418 Phosphorylation
S433 Phosphorylation
Y434 Phosphorylation
S437 Phosphorylation
K451 Acetylation
K460 Acetylation
K460 Ubiquitination
S478 Phosphorylation
T511 Phosphorylation

Research Backgrounds

Function:

Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.

Subcellular Location:

Cell membrane>Lipid-anchor.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Binds PP1.

Restrictive clause

 

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For Research Use Only.
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