PRPF38A Antibody - #DF4329

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Product: PRPF38A Antibody
Catalog: DF4329
Description: Rabbit polyclonal antibody to PRPF38A
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 40 KD; 37kD(Calculated).
Uniprot: Q8NAV1
RRID: AB_2836697

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(80%)
Clonality:
Polyclonal
Specificity:
PRPF38A Antibody detects endogenous levels of total PRPF38A.
RRID:
AB_2836697
Cite Format: Affinity Biosciences Cat# DF4329, RRID:AB_2836697.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

2410002M20Rik; FLJ14936; MGC3320; OTTMUSP00000008592; PR38A_HUMAN; Pre mRNA splicing factor 38A; Pre-mRNA-splicing factor 38A; Prp38; PRP38 pre mRNA processing factor 38 (yeast) domain containing A; PRP38 pre mRNA processing factor 38 domain containing A; prpf38a; RGD1311129; RP23-406B13.4; RP5 965L7.1;

Immunogens

Immunogen:
Uniprot:

Q8NAV1(PR38A_HUMAN) >>Visit HPA database.

Gene(ID):
PRPF38A(84950)
Sequence:
MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
80
Zebrafish
60
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NAV1 As Substrate

Site PTM Type Enzyme
K7 Methylation
K7 Ubiquitination
S11 Phosphorylation
T15 Phosphorylation
K23 Acetylation
K23 Ubiquitination
K66 Ubiquitination
K92 Sumoylation
K97 Acetylation
K97 Ubiquitination
K118 Ubiquitination
K129 Ubiquitination
Y169 Phosphorylation
S182 Phosphorylation
S193 Phosphorylation
S194 Phosphorylation
S209 Phosphorylation
S216 Phosphorylation
S226 Phosphorylation
T228 Phosphorylation
S250 Phosphorylation
S252 Phosphorylation
S260 Phosphorylation
S262 Phosphorylation
S268 Phosphorylation
S270 Phosphorylation
S277 Phosphorylation
S279 Phosphorylation
S281 Phosphorylation
S292 Phosphorylation
S294 Phosphorylation
S296 Phosphorylation

Research Backgrounds

Function:

Involved in pre-mRNA splicing as a component of the spliceosome.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Component of the spliceosome B complex (Probable). Interacts (via N-terminal interaction domain) with ZMAT2 AND MFAP1 (Probable).

Family&Domains:

Belongs to the PRP38 family.

Research Fields

· Genetic Information Processing > Transcription > Spliceosome.

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