PRPF18 Antibody - #DF4328
| Product: | PRPF18 Antibody |
| Catalog: | DF4328 |
| Description: | Rabbit polyclonal antibody to PRPF18 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 40 KD; 40kD(Calculated). |
| Uniprot: | Q99633 |
| RRID: | AB_2836696 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4328, RRID:AB_2836696.
Fold/Unfold
FLJ10210; hPRP18; Pre mRNA splicing factor 18; Pre-mRNA-splicing factor 18; PRP18; PRP18 homolog; PRP18 pre mRNA processing factor 18 homolog (PRPF18); PRP18 pre mRNA processing factor 18 homolog (S. cerevisiae); PRP18_HUMAN; prpf18;
Immunogens
- Q99633 PRP18_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q99633 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K5 | Ubiquitination | Uniprot | |
| Y41 | Phosphorylation | Uniprot | |
| T60 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| T116 | Phosphorylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K247 | Acetylation | Uniprot | |
| T310 | Phosphorylation | Uniprot | |
| K319 | Acetylation | Uniprot |
Research Backgrounds
Participates in the second step of pre-mRNA splicing.
Nucleus speckle.
Note: Colocalizes with spliceosomal snRNPs.
Heterodimer with PPIH. Interacts with PRPF4 and with the spliceosome. Part of a complex containing U4/U6 snRNPs.
Belongs to the PRP18 family.
Research Fields
· Genetic Information Processing > Transcription > Spliceosome.
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