PECI Antibody - #DF4279

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Product: PECI Antibody
Catalog: DF4279
Description: Rabbit polyclonal antibody to PECI
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 40 KD; 44kD(Calculated).
Uniprot: O75521
RRID: AB_2836630

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
PECI Antibody detects endogenous levels of total PECI.
RRID:
AB_2836630
Cite Format: Affinity Biosciences Cat# DF4279, RRID:AB_2836630.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

2-trans-enoyl-CoA isomerase; ACBD2; acyl Coenzyme A binding domain containing 2; D2-enoyl-CoA isomerase; D3; D3 D2 enoyl CoA isomerase; DBI related protein 1; DBI-related protein 1; delta(2)-enoyl-CoA isomerase; Delta(3); Delta(3) delta(2) enoyl CoA isomerase; Diazepam-binding inhibitor-related protein 1; Dodecenoyl CoA isomerase; Dodecenoyl-CoA isomerase; DRS 1; DRS-1; DRS1; Eci2; ECI2_HUMAN; Enoyl-CoA delta isomerase 2; HCA88; Hepatocellular carcinoma associated antigen 88; Hepatocellular carcinoma-associated antigen 88; mitochondrial; pECI; Peroxisomal 3; Peroxisomal 3,2-trans-enoyl-CoA isomerase; Peroxisomal D3 D2 enoyl CoA isomerase; Renal carcinoma antigen NY REN 1; Renal carcinoma antigen NY-REN-1;

Immunogens

Immunogen:
Uniprot:

O75521(ECI2_HUMAN) >>Visit HPA database.

Gene(ID):
ECI2(10455)
Expression:
O75521 ECI2_HUMAN:

Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.

Sequence:
MAMAYLAWRLARRSCPSSLQVTSFPVVQLHMNRTAMRASQKDFENSMNQVKLLKKDPGNEVKLKLYALYKQATEGPCNMPKPGVFDLINKAKWDAWNALGSLPKEAARQNYVDLVSSLSPSLESSSQVEPGTDRKSTGFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGNGDYYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPKIMSPAKATEMLIFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKAFAKLPPNALRISKEVIRKREREKLHAVNAEECNVLQGRWLSDECTNAVVNFLSRKSKL

PTMs - O75521 As Substrate

Site PTM Type Enzyme
S39 Phosphorylation
K41 Acetylation
K51 Acetylation
K54 Acetylation
K62 Acetylation
Y66 Phosphorylation
K92 Acetylation
K92 Ubiquitination
S101 Phosphorylation
K104 Acetylation
S119 Phosphorylation
S121 Phosphorylation
S125 Phosphorylation
K135 Ubiquitination
S136 Phosphorylation
T137 Phosphorylation
K152 Acetylation
K159 Acetylation
K160 Acetylation
T166 Phosphorylation
Y169 Phosphorylation
S278 Phosphorylation
S283 Phosphorylation
S284 Phosphorylation
Y285 Phosphorylation
T286 Phosphorylation
K289 Acetylation
K349 Ubiquitination
K359 Acetylation
K393 Acetylation

Research Backgrounds

Function:

Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity).

Subcellular Location:

Mitochondrion.

Peroxisome matrix.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.

Family&Domains:

In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

Research Fields

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

· Metabolism > Lipid metabolism > Fatty acid degradation.

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