SLC22A3 Antibody - #DF4268
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| Product: | SLC22A3 Antibody |
| Catalog: | DF4268 |
| Description: | Rabbit polyclonal antibody to SLC22A3 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 61 KD; 61kD(Calculated). |
| Uniprot: | O75751 |
| RRID: | AB_2836619 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4268, RRID:AB_2836619.
Fold/Unfold
EMT; EMT organic cation transporter 3; EMTH; Extraneuronal monoamine transporter; OCT 3; OCT3; Orct 3; Orct3; Organic cation transporter 3; S22A3_HUMAN; SLC22 A3; SLC22A 3; Slc22a3; Solute carrier family 22 (extraneuronal monoamine transporter) member 3; Solute carrier family 22 (organic cation transporter) member 3; Solute carrier family 22 member 3;
Immunogens
Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.
- O75751 S22A3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHSCKCGRNKKTPVSRSHL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75751 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S508 | Phosphorylation | Uniprot | |
| T520 | Phosphorylation | Uniprot |
Research Backgrounds
Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.
Membrane>Multi-pass membrane protein.
Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Research Fields
· Human Diseases > Cancers: Overview > Choline metabolism in cancer. (View pathway)
References
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