NUP160 Antibody - #DF4251
(1)
| Product: | NUP160 Antibody |
| Catalog: | DF4251 |
| Description: | Rabbit polyclonal antibody to NUP160 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 140 KD; 162kD(Calculated). |
| Uniprot: | Q12769 |
| RRID: | AB_2836602 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse
Prediction:
Pig(91%), Bovine(100%), Horse(91%), Sheep(100%), Rabbit(82%), Dog(82%)
Clonality:
Polyclonal
Specificity:
NUP160 Antibody detects endogenous levels of total NUP160.
RRID:
AB_2836602
Cite Format: Affinity Biosciences Cat# DF4251, RRID:AB_2836602.
Cite Format: Affinity Biosciences Cat# DF4251, RRID:AB_2836602.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
160 kDa nucleoporin; DKFZp686M14102; FLJ22583; KIAA0197; MGC150678; MGC150679; NU160_HUMAN; Nuclear pore complex protein Nup160; Nucleoporin 160kD; Nucleoporin 160kDa; Nucleoporin Nup160; NUP 160; NUP120; Nup160;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Sequence:
- Q12769 NU160_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLHLSAAPPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSIFTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPYDIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIFALCQDHKLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMGLYLGIYMHAPKRGQFCIFQLVSTESNRYSLDHISSLFTSQETLIDFALTSTDIWALWHDAENQTVVKYINFEHNVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFCRGTERNLDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPLALHLNPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIARDVICLIKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICSKLQEIRNPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIASTRFLICRDLLILQQLLMRLGDAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATDVPLDTLESNLQHLSVLELTDSGALMANRFVSSPQTIVELFFQEVARKHIISHLFSQPKAPLSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQLLHPWCQVNVGSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIRSEDGEIVSTPRLQYYDKVLRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYAWIVQPVSGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHDPSAVAVAGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQAEAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVPLPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQLLQALGENSANSHNIALSQKILDKLEDYQQKVDKATRDLLYRRTL
Predictions
Predictions:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Bovine
100
Sheep
100
Pig
91
Horse
91
Dog
82
Rabbit
82
Zebrafish
70
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q12769 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S44 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| K93 | Ubiquitination | Uniprot | |
| K106 | Acetylation | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| Y246 | Phosphorylation | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| K314 | Acetylation | Uniprot | |
| K343 | Ubiquitination | Uniprot | |
| Y457 | Phosphorylation | Uniprot | |
| S460 | Phosphorylation | Uniprot | |
| T463 | Phosphorylation | Uniprot | |
| T468 | Phosphorylation | Uniprot | |
| R481 | Methylation | Uniprot | |
| S490 | Phosphorylation | Uniprot | |
| K495 | Ubiquitination | Uniprot | |
| K608 | Ubiquitination | Uniprot | |
| T683 | Phosphorylation | Uniprot | |
| K689 | Ubiquitination | Uniprot | |
| K722 | Ubiquitination | Uniprot | |
| Y773 | Phosphorylation | Uniprot | |
| Y774 | Phosphorylation | Uniprot | |
| K833 | Ubiquitination | Uniprot | |
| K925 | Ubiquitination | Uniprot | |
| S935 | Phosphorylation | Uniprot | |
| K939 | Ubiquitination | Uniprot | |
| S949 | Phosphorylation | Uniprot | |
| T957 | Phosphorylation | Uniprot | |
| K965 | Ubiquitination | Uniprot | |
| K995 | Ubiquitination | Uniprot | |
| K1006 | Methylation | Uniprot | |
| K1006 | Ubiquitination | Uniprot | |
| K1096 | Ubiquitination | Uniprot | |
| K1120 | Ubiquitination | Uniprot | |
| Y1139 | Phosphorylation | Uniprot | |
| S1147 | Phosphorylation | Uniprot | |
| Y1151 | Phosphorylation | Uniprot | |
| S1157 | Phosphorylation | Uniprot | |
| K1159 | Ubiquitination | Uniprot | |
| C1166 | S-Nitrosylation | Uniprot | |
| K1185 | Ubiquitination | Uniprot | |
| T1240 | Phosphorylation | Uniprot | |
| K1249 | Ubiquitination | Uniprot | |
| K1252 | Ubiquitination | Uniprot | |
| K1300 | Ubiquitination | Uniprot | |
| K1415 | Ubiquitination | Uniprot | |
| K1422 | Ubiquitination | Uniprot |
Research Backgrounds
Function:
Functions as a component of the nuclear pore complex (NPC). Involved in poly(A)+ RNA transport.
Subcellular Location:
Nucleus>Nuclear pore complex.
Subunit Structure:
Part of the nuclear pore complex (NPC). Forms part of the NUP160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and NUP96. This complex plays a role in RNA export and in tethering NUP98 and NUP153 to the nucleus.
Research Fields
· Genetic Information Processing > Translation > RNA transport.
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