SEPT3 Antibody - #DF4241
| Product: | SEPT3 Antibody |
| Catalog: | DF4241 |
| Description: | Rabbit polyclonal antibody to SEPT3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 41 KD; 41kD(Calculated). |
| Uniprot: | Q9UH03 |
| RRID: | AB_2836592 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4241, RRID:AB_2836592.
Fold/Unfold
bK250D10.3; MGC133218; Neuronal specific septin 3; Neuronal-specific septin-3; OTTHUMP00000028742; SEP 3; SEP3; SEPT 3; sept3; SEPT3 protein; SEPT3_HUMAN; Septin3;
Immunogens
- Q9UH03 SEPT3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSKGLPETRTDAAMSELVPEPRPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVPATPCPTAE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UH03 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K30 | Methylation | Uniprot | |
| S70 | Phosphorylation | Uniprot | |
| S84 | Phosphorylation | Uniprot | |
| S87 | Phosphorylation | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| K226 | Acetylation | Uniprot | |
| K226 | Ubiquitination | Uniprot |
Research Backgrounds
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91 (By similarity).
Cytoplasm. Cytoplasm>Cytoskeleton. Cell junction>Synapse.
Brain-specific.
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity).
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Research Fields
· Human Diseases > Infectious diseases: Bacterial > Bacterial invasion of epithelial cells.
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