NPDC1 Antibody - #DF4225
(1)
(4)
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4225, RRID:AB_2836576.
Fold/Unfold
AI314472; CAB1; Neural proliferation differentiation and control protein 1; NPDC-1; NPDC1; NPDC1_HUMAN;
Immunogens
Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.
- Q9NQX5 NPDC1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATPLPPPSPRHLRLLRLLLSGLVLGAALRGAAAGHPDVAACPGSLDCALKRRARCPPGAHACGPCLQPFQEDQQGLCVPRMRRPPGGGRPQPRLEDEIDFLAQELARKESGHSTPPLPKDRQRLPEPATLGFSARGQGLELGLPSTPGTPTPTPHTSLGSPVSSDPVHMSPLEPRGGQGDGLALVLILAFCVAGAAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERHKEPPKELDTASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHAALSAPLPAPSSPPALP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NQX5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S114 | O-Glycosylation | Uniprot | |
| T115 | O-Glycosylation | Uniprot | |
| T115 | Phosphorylation | Uniprot | |
| T130 | O-Glycosylation | Uniprot | |
| S134 | O-Glycosylation | Uniprot | |
| K218 | Ubiquitination | Uniprot | |
| K225 | Ubiquitination | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| S236 | Phosphorylation | Uniprot | |
| S245 | Phosphorylation | Uniprot | |
| Y249 | Phosphorylation | Uniprot | |
| Y251 | Phosphorylation | Uniprot | |
| S319 | Phosphorylation | Uniprot | |
| S320 | Phosphorylation | Uniprot |
Research Backgrounds
Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation (By similarity).
Membrane>Single-pass membrane protein.
Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.
Belongs to the NPDC1/cab-1 family.
References
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.