SLC16A3 Antibody - #DF4182
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| Product: | SLC16A3 Antibody |
| Catalog: | DF4182 |
| Description: | Rabbit polyclonal antibody to SLC16A3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Rabbit, Xenopus |
| Mol.Wt.: | 49 KD; 49kD(Calculated). |
| Uniprot: | O15427 |
| RRID: | AB_2836547 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4182, RRID:AB_2836547.
Fold/Unfold
MCT 4; MCT3; MCT4; Monocarboxylate transporter 3; Monocarboxylate transporter 4; MOT4_HUMAN; SLC16A3; Solute carrier family 16 member 3;
Immunogens
- O15427 MOT4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15427 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S35 | Phosphorylation | Uniprot | |
| Y36 | Phosphorylation | Uniprot | |
| K254 | Sumoylation | Uniprot | |
| K262 | Sumoylation | Uniprot | |
| K415 | Ubiquitination | Uniprot | |
| K428 | Ubiquitination | Uniprot | |
| K431 | Ubiquitination | Uniprot | |
| S436 | Phosphorylation | Uniprot | |
| K448 | Sumoylation | Uniprot | |
| K448 | Ubiquitination | Uniprot | |
| K453 | Ubiquitination | Uniprot | |
| T460 | Phosphorylation | Uniprot | |
| T463 | Phosphorylation | Uniprot | |
| S464 | Phosphorylation | Uniprot |
Research Backgrounds
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Cell membrane>Multi-pass membrane protein.
Highly expressed in skeletal muscle.
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Research Fields
· Human Diseases > Cancers: Overview > Central carbon metabolism in cancer. (View pathway)
References
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