LSP1 Antibody - #DF4148

(3)  
Product: LSP1 Antibody
Catalog: DF4148
Description: Rabbit polyclonal antibody to LSP1
Application: WB IHC IF/ICC
Reactivity: Human
Prediction: Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus
Mol.Wt.: 37 KD; 37kD(Calculated).
Uniprot: P33241
RRID: AB_2836513

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(92%), Zebrafish(92%), Bovine(92%), Dog(100%), Chicken(83%), Xenopus(83%)
Clonality:
Polyclonal
Specificity:
LSP1 Antibody detects endogenous levels of total LSP1.
RRID:
AB_2836513
Cite Format: Affinity Biosciences Cat# DF4148, RRID:AB_2836513.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

47 kDa actin binding protein; 47 kDa actin-binding protein; 52 kDa phosphoprotein; F actin binding and cytoskeleton associated protein; Leufactin (leukocyte F-actin binding protein); Leufactin; Leukocyte F actin binding protein; Leukocyte specific protein 1; LSP 1; Lsp1; LSP1_HUMAN; Lymphocyte specific antigen WP34; Lymphocyte specific protein 1; Lymphocyte specific protein pp52; Lymphocyte-specific antigen WP34; Lymphocyte-specific protein 1; OTTHUMP00000014138; OTTHUMP00000014139; OTTHUMP00000014140; OTTHUMP00000069612; OTTHUMP00000069614; OTTHUMP00000069615; OTTHUMP00000069616; pp52; Protein pp52; S37 protein; WP 34; WP34;

Immunogens

Immunogen:
Uniprot:

P33241(LSP1_HUMAN) >>Visit HPA database.

Gene(ID):
LSP1(4046)
Expression:
P33241 LSP1_HUMAN:

Activated T-lymphocytes.

Sequence:
MAEASSDPGAEEREELLGPTAQWSVEDEEEAVHEQCQHERDRQLQAQDEEGGGHVPERPKQEMLLSLKPSEAPELDEDEGFGDWSQRPEQRQQHEGAQGALDSGEPPQCRSPEGEQEDRPGLHAYEKEDSDEVHLEELSLSKEGPGPEDTVQDNLGAAGAEEEQEEHQKCQQPRTPSPLVLEGTIEQSSPPLSPTTKLIDRTESLNRSIEKSNSVKKSQPDLPISKIDQWLEQYTQAIETAGRTPKLARQASIELPSMAVASTKSRWETGEVQAQSAAKTPSCKDIVAGDMSKKSLWEQKGGSKTSSTIKSTPSGKRYKFVATGHGKYEKVLVEGGPAP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Pig
92
Bovine
92
Zebrafish
92
Xenopus
83
Chicken
83
Horse
0
Sheep
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P33241 As Substrate

Site PTM Type Enzyme
S6 Phosphorylation
T20 Phosphorylation
S24 Phosphorylation
K60 Ubiquitination
S66 Phosphorylation
K68 Ubiquitination
S103 Phosphorylation
S111 Phosphorylation
Y125 Phosphorylation
S130 Phosphorylation
S139 Phosphorylation
S141 Phosphorylation
T175 Phosphorylation
S177 Phosphorylation
T184 Phosphorylation
S188 Phosphorylation
S189 Phosphorylation
S193 Phosphorylation
T195 Phosphorylation
T196 Phosphorylation
T202 Phosphorylation
S204 Phosphorylation P49137 (MAPKAPK2)
S208 Phosphorylation
S218 Phosphorylation
K226 Ubiquitination
Y234 Phosphorylation
T235 Phosphorylation
T244 Phosphorylation
S252 Phosphorylation P49137 (MAPKAPK2)
S257 Phosphorylation
S262 Phosphorylation
S265 Phosphorylation
T269 Phosphorylation
S282 Phosphorylation
S292 Phosphorylation
T323 Phosphorylation
K327 Acetylation
Y328 Phosphorylation

Research Backgrounds

Function:

May play a role in mediating neutrophil activation and chemotaxis.

PTMs:

Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis (By similarity).

Subcellular Location:

Cell membrane>Peripheral membrane protein>Cytoplasmic side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Activated T-lymphocytes.

Subunit Structure:

Binds actin.

Research Fields

· Human Diseases > Infectious diseases: Bacterial > Tuberculosis.

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