Msx2/Hox8 Antibody - #DF4126
| Product: | Msx2/Hox8 Antibody |
| Catalog: | DF4126 |
| Description: | Rabbit polyclonal antibody to Msx2/Hox8 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus |
| Mol.Wt.: | 29 KD; 29kD(Calculated). |
| Uniprot: | P35548 |
| RRID: | AB_2836491 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4126, RRID:AB_2836491.
Fold/Unfold
CRS 2; CRS2; FPP; Homeo box msh like 2; Homeobox protein Hox-8; Homeobox protein MSX 2; Homeobox protein MSX-2; Homeobox protein MSX2; Hox 8; Hox8; MSH; Msh homeo box 2; Msh homeo box homolog; Msh homeo box homolog 2; Msh homeobox 2; Msh homeobox homolog 2; Msx 2; MSX2; MSX2_HUMAN; Parietal foramina 1; PFM 1; PFM; PFM1;
Immunogens
- P35548 MSX2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P35548 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S63 | Phosphorylation | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| Y122 | Phosphorylation | Uniprot | |
| S123 | Phosphorylation | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| T135 | Phosphorylation | P05771 (PRKCB) | Uniprot |
| T141 | Phosphorylation | P05771 (PRKCB) | Uniprot |
| K160 | Acetylation | Uniprot | |
| K164 | Acetylation | Uniprot | |
| K207 | Ubiquitination | Uniprot |
Research Backgrounds
Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
Nucleus.
Interacts with MINT (By similarity). Interacts with XRCC6 (Ku70) and XRCC5 (Ku80).
Belongs to the Msh homeobox family.
Research Fields
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
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