Product: GHITM Antibody
Catalog: DF4093
Description: Rabbit polyclonal antibody to GHITM
Application: WB IHC IF/ICC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 37 KD; 37kD(Calculated).
Uniprot: Q9H3K2
RRID: AB_2836467

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%), Horse(91%), Sheep(100%), Rabbit(100%), Dog(82%)
Clonality:
Polyclonal
Specificity:
GHITM Antibody detects endogenous levels of total GHITM.
RRID:
AB_2836467
Cite Format: Affinity Biosciences Cat# DF4093, RRID:AB_2836467.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Dermal papilla derived protein 2; Dermal papilla-derived protein 2; DERP2; Ghitm; GHITM_HUMAN; Growth hormone inducible transmembrane protein; Growth hormone-inducible transmembrane protein; HSPC282; MICS1; Mitochondrial morphology and cristae structure 1; My021; PTD010; TMBIM5; Transmembrane BAX inhibitor motif containing 5; Transmembrane BAX inhibitor motif containing protein 5; Transmembrane BAX inhibitor motif-containing protein 5;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MLAARLVCLRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYATKTRIGIRRGRTGQELKEAALEPSMEKIFKIDQMGRWFVAGGAAVGLGALCYYGLGLSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLTALSAIAISRTPVLMNFMMRGSWVTIGVTFAAMVGAGMLVRSIPYDQSPGPKHLAWLLHSGVMGAVVAPLTILGGPLLIRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSSLGSMFLPPTTVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYMDTLNIFMRVATMLATGGNRKK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Rabbit
100
Horse
91
Dog
82
Xenopus
75
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H3K2 As Substrate

Site PTM Type Enzyme
K23 Ubiquitination
K29 Ubiquitination
K34 Ubiquitination
T40 Phosphorylation
K63 Ubiquitination
S70 Phosphorylation
K73 Ubiquitination
S185 Phosphorylation
Y313 Phosphorylation

Research Backgrounds

Function:

Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.

Subcellular Location:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the BI1 family.

Restrictive clause

 

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For Research Use Only.
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