Product: ENDOGL1 Antibody
Catalog: DF4040
Description: Rabbit polyclonal antibody to ENDOGL1
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Sheep, Dog, Chicken
Mol.Wt.: 41 KD; 41kD(Calculated).
Uniprot: Q9Y2C4
RRID: AB_2836393

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(80%), Bovine(80%), Sheep(80%), Dog(80%), Chicken(80%)
Clonality:
Polyclonal
Specificity:
ENDOGL1 Antibody detects endogenous levels of total ENDOGL1.
RRID:
AB_2836393
Cite Format: Affinity Biosciences Cat# DF4040, RRID:AB_2836393.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Endo G like 1; Endo G-like 1; Endo/exonuclease (5'-3'), endonuclease G like; ENDOGL 1; ENDOGL1; ENDOGL2; Endonuclease G like 1; Endonuclease G like 2; Endonuclease G-like 1; ENGL a; ENGL; ENGL B; ENGLA; ENGLB; Exog; EXOG_HUMAN; MGC125944; MGC125945; mitochondrial; Nuclease EXOG; Nuclease EXOG mitochondrial;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9Y2C4 EXOG_HUMAN:

Ubiquitous.

Sequence:
MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
80
Bovine
80
Sheep
80
Dog
80
Chicken
80
Horse
70
Zebrafish
67
Xenopus
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y2C4 As Substrate

Site PTM Type Enzyme
K4 Ubiquitination
S5 Phosphorylation
K59 Acetylation
K100 Acetylation
K230 Ubiquitination
K327 Ubiquitination
K333 Ubiquitination
K350 Ubiquitination
K355 Ubiquitination

Research Backgrounds

Function:

Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.

Subcellular Location:

Mitochondrion inner membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the DNA/RNA non-specific endonuclease family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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