DZIP3 Antibody - #DF4017
| Product: | DZIP3 Antibody |
| Catalog: | DF4017 |
| Description: | Rabbit polyclonal antibody to DZIP3 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Rat |
| Prediction: | Pig, Horse, Rabbit, Dog |
| Mol.Wt.: | 139 KD; 139kD(Calculated). |
| Uniprot: | Q86Y13 |
| RRID: | AB_2836377 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4017, RRID:AB_2836377.
Fold/Unfold
DAZ-interacting protein 3; E3 ubiquitin-protein ligase DZIP3; hRUL138; KIAA0675; RNA-binding ubiquitin ligase of 138 kDa;
Immunogens
Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
- Q86Y13 DZIP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNAINTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQAGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSLVYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIKTTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKYPGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLISLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPLLKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVFPAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRLGMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIEIEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQRKKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFYSLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQENQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHNLESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEILMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVPPSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKISQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDEEEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGHPSRQLPKI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q86Y13 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| T229 | Phosphorylation | Uniprot | |
| T242 | Phosphorylation | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| K311 | Ubiquitination | Uniprot | |
| K315 | Ubiquitination | Uniprot | |
| T319 | Phosphorylation | Uniprot | |
| K363 | Ubiquitination | Uniprot | |
| K372 | Ubiquitination | Uniprot | |
| K376 | Ubiquitination | Uniprot | |
| K380 | Ubiquitination | Uniprot | |
| Y392 | Phosphorylation | Uniprot | |
| K484 | Ubiquitination | Uniprot | |
| K485 | Ubiquitination | Uniprot | |
| K498 | Ubiquitination | Uniprot | |
| S612 | Phosphorylation | Uniprot | |
| K635 | Ubiquitination | Uniprot | |
| S644 | Phosphorylation | Uniprot | |
| K663 | Acetylation | Uniprot | |
| K664 | Acetylation | Uniprot | |
| K684 | Ubiquitination | Uniprot | |
| K690 | Ubiquitination | Uniprot | |
| K703 | Ubiquitination | Uniprot | |
| S707 | Phosphorylation | Uniprot | |
| K718 | Ubiquitination | Uniprot | |
| K738 | Ubiquitination | Uniprot | |
| K748 | Ubiquitination | Uniprot | |
| K759 | Ubiquitination | Uniprot | |
| K768 | Methylation | Uniprot | |
| K768 | Ubiquitination | Uniprot | |
| K786 | Ubiquitination | Uniprot | |
| K816 | Ubiquitination | Uniprot | |
| K821 | Ubiquitination | Uniprot | |
| K824 | Ubiquitination | Uniprot | |
| K830 | Ubiquitination | Uniprot | |
| K838 | Ubiquitination | Uniprot | |
| K846 | Ubiquitination | Uniprot | |
| K851 | Ubiquitination | Uniprot | |
| K883 | Ubiquitination | Uniprot | |
| K936 | Ubiquitination | Uniprot | |
| K1042 | Ubiquitination | Uniprot | |
| K1051 | Ubiquitination | Uniprot | |
| T1054 | Phosphorylation | Uniprot | |
| K1061 | Ubiquitination | Uniprot | |
| K1066 | Ubiquitination | Uniprot | |
| S1081 | Phosphorylation | Uniprot | |
| K1087 | Ubiquitination | Uniprot | |
| K1088 | Ubiquitination | Uniprot | |
| S1097 | Phosphorylation | Uniprot | |
| S1103 | Phosphorylation | Uniprot | |
| K1118 | Ubiquitination | Uniprot |
Research Backgrounds
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
Cytoplasm.
Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
Interacts with DAZ proteins.
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