NT5C1A Antibody - #DF3978
| Product: | NT5C1A Antibody |
| Catalog: | DF3978 |
| Description: | Rabbit polyclonal antibody to NT5C1A |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 41 KD; 41kD(Calculated). |
| Uniprot: | Q9BXI3 |
| RRID: | AB_2836338 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3978, RRID:AB_2836338.
Fold/Unfold
5' nucleotidase cytosolic IA; 5NT1A_HUMAN; AMP specific 5' NT; CN I; CN IA; cN-I; cN-IA; CN1; cN1A; cNI; cNIA; Cytosolic 5' nucleotidase 1A; Cytosolic 5' nucleotidase IA; Cytosolic 5' nucleotidase type 1A; Cytosolic 5''-nucleotidase 1A; Cytosolic 5''-nucleotidase IA; MGC119199; MGC119201; NT5C1A; nucleotidase, 5-prime, cytosolic, IA;
Immunogens
Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.
- Q9BXI3 5NT1A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTAPAKQAPSAQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BXI3 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K31 | Acetylation | Uniprot | |
| Y34 | Phosphorylation | Uniprot | |
| S57 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| Y79 | Phosphorylation | Uniprot | |
| Y265 | Phosphorylation | Uniprot | |
| S266 | Phosphorylation | Uniprot | |
| K314 | Acetylation | Uniprot |
Research Backgrounds
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.
Cytoplasm.
Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.
Belongs to the 5'-nucleotidase type 3 family.
Research Fields
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Metabolism of cofactors and vitamins > Nicotinate and nicotinamide metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.