Product: CKLF3 Antibody
Catalog: DF3943
Description: Rabbit polyclonal antibody to CKLF3
Application: WB IHC IF/ICC
Reactivity: Human
Prediction: Rabbit
Mol.Wt.: 22 KD; 20kD(Calculated).
Uniprot: Q96MX0
RRID: AB_2836296

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Rabbit(100%)
Clonality:
Polyclonal
Specificity:
CKLF3 Antibody detects endogenous levels of total CKLF3.
RRID:
AB_2836296
Cite Format: Affinity Biosciences Cat# DF3943, RRID:AB_2836296.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

9430096L06Rik; AI413895; BNAS2; Chemokine like factor super family 3; Chemokine like factor superfamily member 3; CKLF like MARVEL transmembrane domain containing 3; CKLF like MARVEL transmembrane domain containing protein 3; CKLFSF3; CMTM 3; FLJ31762; MGC51956;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q96MX0 CKLF3_HUMAN:

Expressed in the leukocytes, placenta and testis.

Sequence:
MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYVASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITAIAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSDSD

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Dog
50
Pig
0
Horse
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96MX0 As Substrate

Site PTM Type Enzyme
K159 Ubiquitination

Research Backgrounds

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in the leukocytes, placenta and testis.

Family&Domains:

Belongs to the chemokine-like factor family.

References

1). In vivo study revealed pro-tumorigenic effect of CMTM3 in hepatocellular carcinoma involving the regulation of peroxisome proliferator-activated receptor gamma (PPARγ). Cellular Oncology, 2022 (PubMed: 36284038) [IF=6.6]

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For Research Use Only.
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