Product: CSGLCAT Antibody
Catalog: DF3937
Description: Rabbit polyclonal antibody to CSGLCAT
Application: WB IF/ICC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Dog
Mol.Wt.: 86 KD; 86kD(Calculated).
Uniprot: Q9P2E5
RRID: AB_2836290

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(82%), Bovine(82%), Horse(91%), Sheep(82%), Dog(82%)
Clonality:
Polyclonal
Specificity:
CSGLCAT Antibody detects endogenous levels of total CSGLCAT.
RRID:
AB_2836290
Cite Format: Affinity Biosciences Cat# DF3937, RRID:AB_2836290.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Chondroitin glucuronyltransferase; Chondroitin polymerizing factor 2; Chondroitin sulfate glucuronyltransferase; Chondroitin synthase 3; ChPF-2; CHPF2; CHPF2_HUMAN; ChSy 3; ChSy-3; CSGLCA T; CSGlcA-T; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9P2E5 CHPF2_HUMAN:

Ubiquitous. Highly expressed in placenta, small intestine and pancreas.

Sequence:
MRLSSLLALLRPALPLILGLSLGCSLSLLRVSWIQGEGEDPCVEAVGERGGPQNPDSRARLDQSDEDFKPRIVPYYRDPNKPYKKVLRTRYIQTELGSRERLLVAVLTSRATLSTLAVAVNRTVAHHFPRLLYFTGQRGARAPAGMQVVSHGDERPAWLMSETLRHLHTHFGADYDWFFIMQDDTYVQAPRLAALAGHLSINQDLYLGRAEEFIGAGEQARYCHGGFGYLLSRSLLLRLRPHLDGCRGDILSARPDEWLGRCLIDSLGVGCVSQHQGQQYRSFELAKNRDPEKEGSSAFLSAFAVHPVSEGTLMYRLHKRFSALELERAYSEIEQLQAQIRNLTVLTPEGEAGLSWPVGLPAPFTPHSRFEVLGWDYFTEQHTFSCADGAPKCPLQGASRADVGDALETALEQLNRRYQPRLRFQKQRLLNGYRRFDPARGMEYTLDLLLECVTQRGHRRALARRVSLLRPLSRVEILPMPYVTEATRVQLVLPLLVAEAAAAPAFLEAFAANVLEPREHALLTLLLVYGPREGGRGAPDPFLGVKAAAAELERRYPGTRLAWLAVRAEAPSQVRLMDVVSKKHPVDTLFFLTTVWTRPGPEVLNRCRMNAISGWQAFFPVHFQEFNPALSPQRSPPGPPGAGPDPPSPPGADPSRGAPIGGRFDRQASAEGCFYNADYLAARARLAGELAGQEEEEALEGLEVMDVFLRFSGLHLFRAVEPGLVQKFSLRDCSPRLSEELYHRCRLSNLEGLGGRAQLAMALFEQEQANST

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
91
Pig
82
Bovine
82
Sheep
82
Dog
82
Rabbit
73
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9P2E5 As Substrate

Site PTM Type Enzyme
S64 Phosphorylation
K69 Ubiquitination
Y83 Phosphorylation
T89 Phosphorylation
S301 Phosphorylation
Y315 Phosphorylation
K546 Ubiquitination
K727 Ubiquitination
S729 Phosphorylation

Research Backgrounds

Function:

Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity.

Subcellular Location:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous. Highly expressed in placenta, small intestine and pancreas.

Family&Domains:

Belongs to the chondroitin N-acetylgalactosaminyltransferase family.

Research Fields

· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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