ARPP21 Antibody - #DF3871
| Product: | ARPP21 Antibody |
| Catalog: | DF3871 |
| Description: | Rabbit polyclonal antibody to ARPP21 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 80 KD; 89kD(Calculated). |
| Uniprot: | Q9UBL0 |
| RRID: | AB_2836224 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3871, RRID:AB_2836224.
Fold/Unfold
0710001E13Rik; AI853636; ARP21_HUMAN; ARPP-21; ARPP21; cAMP regulated phosphoprotein, 21kDa; cAMP-regulated phosphoprotein 21; cAMP-regulated phosphoprotein, 21-KD; Cyclic AMP-regulated phosphoprotein; Cyclic AMP-regulated phosphoprotein, 21; D9Bwg1012e; FLJ32997; MGC109368; OTTHUMP00000161358; OTTHUMP00000208635; OTTHUMP00000208636; OTTHUMP00000208637; OTTHUMP00000208638; OTTHUMP00000208639; OTTHUMP00000208640; OTTHUMP00000208641; OTTHUMP00000208646; OTTHUMP00000208648; OTTHUMP00000208651; OTTHUMP00000208652; OTTHUMP00000208653; OTTHUMP00000208657; Ppp1r1c; Ppp1r1cl; R3H domain containing 3; R3HDM3; RCS; Regulator of calmodulin signaling; RGD1307208; RGD1307215; Tarpp; Thymocyte cAMP-regulated phosphoprotein;
Immunogens
Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level).
- Q9UBL0 ARP21_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEQGDLNQAIAEEGGTEQETATPENGIVKSESLDEEEKLELQRRLEAQNQERRKSKSGAGKGKLTRSLAVCEESSARPGGESLQDQESIHLQLSSFSSLQEEDKSRKDDSEREKEKDKNKDKTSEKPKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNSRDRMILLKMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTGKSVIINKTSSTRIPEQRFCEHLKDEKGEESQKRFILKRDNSSIDKEDNQQNRMHPFRDDRRSKSIEEREEEYQRVRERIFAHDSVCSQESLFVENSRLLEDSNICNETYKKRQLFRGNRDGSGRTSGSRQSSSENELKWSDHQRAWSSTDSDSSNRNLKPAMTKTASFGGITVLTRGDSTSSTRSTGKLSKAGSESSSSAGSSGSLSRTHPPLQSTPLVSGVAAGSPGCVPYPENGIGGQVAPSSTSYILLPLEAATGIPPGSILLNPHTGQPFVNPDGTPAIYNPPTSQQPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMAGPLVTQRDDVATQFGQMTLSRQSSGETPEPPSGPVYPSSLMPQPAQQPSYVIASTGQQLPTGGFSGSGPPISQQVLQPPPSPQGFVQQPPPAQMPVYYYPSGQYPTSTTQQYRPMAPVQYNAQRSQQMPQAAQQAGYQPVLSGQQGFQGLIGVQQPPQSQNVINNQQGTPVQSVMVSYPTMSSYQVPMTQGSQGLPQQSYQQPIMLPNQAGQGSLPATGMPVYCNVTPPTPQNNLRLIGPHCPSSTVPVMSASCRTNCASMSNAGWQVKF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UBL0 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S33 | Phosphorylation | Uniprot | |
| K39 | Ubiquitination | Uniprot | |
| K57 | Acetylation | Uniprot | |
| S58 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| K62 | Acetylation | Uniprot | |
| K64 | Acetylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| S134 | Phosphorylation | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| Y141 | Phosphorylation | Uniprot | |
| T156 | Phosphorylation | Uniprot | |
| K158 | Ubiquitination | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| T215 | Phosphorylation | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| K223 | Ubiquitination | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| R284 | Methylation | Uniprot | |
| Y288 | Phosphorylation | Uniprot | |
| K326 | Ubiquitination | Uniprot | |
| S338 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| S367 | Phosphorylation | Uniprot | |
| K375 | Ubiquitination | Uniprot | |
| T381 | Phosphorylation | Uniprot | |
| S383 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| S410 | Phosphorylation | Uniprot | |
| S414 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| S421 | Phosphorylation | Uniprot | |
| S562 | Phosphorylation | Uniprot | |
| R655 | Methylation | Uniprot |
Research Backgrounds
Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.
Phosphorylation at Ser-56 favors interaction with CALM1.
Isoform 1 is methylated by CARM1 in immature thymocytes.
Cytoplasm.
Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level).
Interacts with CALM1.
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