Product: BAIAP2L2 Antibody
Catalog: DF3854
Description: Rabbit polyclonal antibody to BAIAP2L2
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Dog, Chicken
Mol.Wt.: 52 KD; 59kD(Calculated).
Uniprot: Q6UXY1
RRID: AB_2836211

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(90%), Sheep(100%), Dog(100%), Chicken(91%)
Clonality:
Polyclonal
Specificity:
BAIAP2L2 Antibody detects endogenous levels of total BAIAP2L2.
RRID:
AB_2836211
Cite Format: Affinity Biosciences Cat# DF3854, RRID:AB_2836211.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BAI1-associated protein 2-like 2; BAI1-associated protein 2-like protein 2; baiap2l2; BAIAP2L2 BAI1-associated protein 2-like 2; BC048937; BI2L2_HUMAN; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; FLJ22582; Pinkbar; Planar intestinal- and kidney-specific BAR domain protein; RP5-1039K5.3;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q6UXY1 BI2L2_HUMAN:

Expressed in the epithelial layer of the intestine (at protein level).

Sequence:
MAPEMDQFYRSTMAIYKSIMEQFNPALENLVYLGNNYLRAFHALSEAAEVYFSAIQKIGERALQSPTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGGLLQHMEKNTKLDMQFIKDSRQHYELEYRHRAANLEKCMSELWRMERKRDKNVREMKESVNRLHAQMQAFVSESQRAAELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQSEASRSPSRAHSPGLLGPALGPPYPSGRLTPTCLDMPPRPLGEFSSPRSRHGSGSYGTEPDARPASQLEPDRRSLPRTPSASSLYSGSAQSSRSNSFGERPGGGGGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSASGWFPEAYVKALEEGPVNPMTPVTPMTSMTSMSPMTPMNPGNELPSRSYPLRGSHSLDDLLDRPGNSIAPSEYWDGQSRSRTPSRVPSRAPSPAPPPLPSSRRSSMGSTAVATDVKKLMSSEQYPPQELFPRGTNPFATVKLRPTITNDRSAPLIR

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Chicken
91
Horse
90
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6UXY1 As Substrate

Site PTM Type Enzyme
S231 Phosphorylation
S264 Phosphorylation
S272 Phosphorylation
S293 Phosphorylation
T297 Phosphorylation
S299 Phosphorylation
S301 Phosphorylation
Y304 Phosphorylation
S315 Phosphorylation
S336 Phosphorylation
S427 Phosphorylation
S429 Phosphorylation
S453 Phosphorylation
T455 Phosphorylation
S457 Phosphorylation
S461 Phosphorylation
S465 Phosphorylation
S477 Phosphorylation
S478 Phosphorylation
T512 Phosphorylation

Research Backgrounds

Function:

Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity).

Subcellular Location:

Cell membrane>Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane.
Note: Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in the epithelial layer of the intestine (at protein level).

Family&Domains:

The IMD domain consisting of an antiparallel dimer of three-helix bundles, featuring on one side a positively charged. The N-terminal alpha-helix inserts into the lipid bilayer. Also forms homodimers and homooligomers. The residue Trp-141 is essential for oligomer formation (By similarity).

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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