ABCF1 Antibody - #DF3815
| Product: | ABCF1 Antibody |
| Catalog: | DF3815 |
| Description: | Rabbit polyclonal antibody to ABCF1 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 95kDa; 96kD(Calculated). |
| Uniprot: | Q8NE71 |
| RRID: | AB_2836172 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3815, RRID:AB_2836172.
Fold/Unfold
ABC27; ABC50; ABCF1; ABCF1_HUMAN; ATP binding cassette 50 (TNF alpha stimulated); ATP binding cassette 50; ATP binding cassette sub family F member 1; ATP binding cassette, sub family F (GCN20), member 1; ATP-binding cassette 50; ATP-binding cassette sub-family F member 1; AU041969; D17Wsu166e; EST123147; GCN20; TNF alpha stimulated ABC protein; TNF-alpha-stimulated ABC protein; TNFalpha inducible ATP binding protein; wu:fb79c06; wu:fc39a05; wu:fj94a08; zgc:85667;
Immunogens
- Q8NE71 ABCF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMVSRPRE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8NE71 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K6 | Ubiquitination | Uniprot | |
| S20 | Phosphorylation | Uniprot | |
| T21 | Phosphorylation | Uniprot | |
| S22 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| K39 | Ubiquitination | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| T108 | Phosphorylation | Uniprot | |
| S109 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| S140 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| K163 | Acetylation | Uniprot | |
| K163 | Methylation | Uniprot | |
| S166 | Phosphorylation | Uniprot | |
| K174 | Methylation | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| K176 | Methylation | Uniprot | |
| K209 | Ubiquitination | Uniprot | |
| S228 | Phosphorylation | Uniprot | |
| S244 | Phosphorylation | Uniprot | |
| Y250 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| K255 | Ubiquitination | Uniprot | |
| K263 | Ubiquitination | Uniprot | |
| Y267 | Phosphorylation | Uniprot | |
| S273 | Phosphorylation | Uniprot | |
| K275 | Methylation | Uniprot | |
| K275 | Ubiquitination | Uniprot | |
| S287 | Phosphorylation | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| Y332 | Phosphorylation | Uniprot | |
| T343 | Phosphorylation | Uniprot | |
| T344 | Phosphorylation | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| K389 | Ubiquitination | Uniprot | |
| T407 | Phosphorylation | Uniprot | |
| K414 | Ubiquitination | Uniprot | |
| Y416 | Phosphorylation | Uniprot | |
| T422 | Phosphorylation | Uniprot | |
| K430 | Ubiquitination | Uniprot | |
| K451 | Ubiquitination | Uniprot | |
| K537 | Methylation | Uniprot | |
| K549 | Ubiquitination | Uniprot | |
| Y551 | Phosphorylation | Uniprot | |
| K573 | Ubiquitination | Uniprot | |
| K576 | Ubiquitination | Uniprot | |
| T580 | Phosphorylation | Uniprot | |
| K582 | Ubiquitination | Uniprot | |
| K589 | Ubiquitination | Uniprot | |
| S595 | Phosphorylation | Uniprot | |
| K603 | Ubiquitination | Uniprot | |
| S621 | Phosphorylation | Uniprot | |
| S652 | Phosphorylation | Uniprot | |
| S665 | Phosphorylation | Uniprot | |
| T666 | Phosphorylation | Uniprot | |
| T672 | Phosphorylation | Uniprot | |
| T676 | Phosphorylation | Uniprot | |
| T678 | Phosphorylation | Uniprot | |
| K689 | Ubiquitination | Uniprot | |
| Y710 | Phosphorylation | Uniprot | |
| K748 | Ubiquitination | Uniprot |
Research Backgrounds
Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes.
Cytoplasm. Nucleus>Nucleoplasm. Nucleus envelope.
Ubiquitous.
Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes.
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
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