ARSG Antibody - #DF3797
| Product: | ARSG Antibody |
| Catalog: | DF3797 |
| Description: | Rabbit polyclonal antibody to ARSG |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Rabbit |
| Mol.Wt.: | 65 KD; 57kD(Calculated). |
| Uniprot: | Q96EG1 |
| RRID: | AB_2836154 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3797, RRID:AB_2836154.
Fold/Unfold
Arsg; ARSG_HUMAN; Arylsulfatase G; Arylsulfatase G precursor; ASG; KIAA1001; PRO1777; UNQ839;
Immunogens
Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.
- Q96EG1 ARSG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96EG1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S69 | Phosphorylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| Y204 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| K451 | Ubiquitination | Uniprot |
Research Backgrounds
Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate.
N-glycosylated.
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Glycosylated.
Lysosome.
Note: Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins.
Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.
Belongs to the sulfatase family.
Research Fields
· Cellular Processes > Transport and catabolism > Lysosome. (View pathway)
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