APPBP2 Antibody - #DF3771
| Product: | APPBP2 Antibody |
| Catalog: | DF3771 |
| Description: | Rabbit polyclonal antibody to APPBP2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 67 KD; 67kD(Calculated). |
| Uniprot: | Q92624 |
| RRID: | AB_2836135 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3771, RRID:AB_2836135.
Fold/Unfold
amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Protein interacting with APP tail 1;
Immunogens
- Q92624 APBP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q92624 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K68 | Methylation | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| S106 | Phosphorylation | Uniprot | |
| K178 | Ubiquitination | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K195 | Ubiquitination | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| T237 | Phosphorylation | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| K283 | Ubiquitination | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| K396 | Ubiquitination | Uniprot | |
| K418 | Ubiquitination | Uniprot | |
| K419 | Ubiquitination | Uniprot | |
| K430 | Ubiquitination | Uniprot | |
| K446 | Ubiquitination | Uniprot | |
| K454 | Ubiquitination | Uniprot | |
| K504 | Ubiquitination | Uniprot | |
| Y517 | Phosphorylation | Uniprot | |
| K522 | Ubiquitination | Uniprot |
Research Backgrounds
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.
Nucleus. Cytoplasm>Cytoskeleton. Membrane>Peripheral membrane protein.
Note: Associated with membranes and microtubules.
Binds APP.
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