AMPD2 Antibody - #DF3766

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Product: AMPD2 Antibody
Catalog: DF3766
Description: Rabbit polyclonal antibody to AMPD2
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 100 KD; 101kD(Calculated).
Uniprot: Q01433
RRID: AB_2836130

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(91%)
Clonality:
Polyclonal
Specificity:
AMPD2 Antibody detects endogenous levels of total AMPD2.
RRID:
AB_2836130
Cite Format: Affinity Biosciences Cat# DF3766, RRID:AB_2836130.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Adenosine monophosphate deaminase 2 (isoform L); Adenosine monophosphate deaminase 2; adenosine monophosphate deaminase 2 isoform L; AMP deaminase 2; AMP deaminase isoform L; AMPD 2; AMPD; AMPD2; AMPD2_HUMAN; RP5-1160K1.5; SPG63;

Immunogens

Immunogen:
Uniprot:

Q01433(AMPD2_HUMAN) >>Visit HPA database.

Gene(ID):
AMPD2(271)
Expression:
Q01433 AMPD2_HUMAN:

Highly expressed in cerebellum.

Sequence:
MRNRGQGLFRLRSRCFLHQSLPLGAGRRKGLDVAEPGPSRCRSDSPAVAAVVPAMASYPSGSGKPKAKYPFKKRASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFPLDLRTSMDGKCKEIAEELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
91
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q01433 As Substrate

Site PTM Type Enzyme
R2 Methylation
R4 Methylation
Q6 Methylation
S13 Phosphorylation
S43 Phosphorylation
S45 Phosphorylation
S60 Phosphorylation
S76 Phosphorylation
R87 Methylation
S97 Phosphorylation
R99 Methylation
S100 Phosphorylation
K109 Ubiquitination
T117 Phosphorylation
S118 Phosphorylation
K124 Ubiquitination
S134 Phosphorylation
S138 Phosphorylation
S142 Phosphorylation
Y145 Phosphorylation
S151 Phosphorylation
S168 Phosphorylation
K182 Ubiquitination
K187 Ubiquitination
T188 Phosphorylation
S190 Phosphorylation
S192 Phosphorylation
Y197 Phosphorylation
K198 Ubiquitination
S208 Phosphorylation
K229 Ubiquitination
C230 S-Nitrosylation
K242 Ubiquitination
Y254 Phosphorylation
K276 Ubiquitination
T289 Phosphorylation
S292 Phosphorylation
Y307 Phosphorylation
T314 Phosphorylation
K372 Sumoylation
K414 Ubiquitination
K489 Ubiquitination
K493 Ubiquitination
Y494 Phosphorylation
S500 Phosphorylation
K508 Ubiquitination
T509 Phosphorylation
K516 Acetylation
S527 Phosphorylation
K533 Ubiquitination
Y721 Phosphorylation
K812 Ubiquitination
R839 Methylation
S875 Phosphorylation

Research Backgrounds

Function:

AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.

PTMs:

Methylated at Gln-6 by N6AMT1.

Tissue Specificity:

Highly expressed in cerebellum.

Subunit Structure:

Homotetramer.

Family&Domains:

Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

Research Fields

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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