SLC25A31 Antibody - #DF3743

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Product: SLC25A31 Antibody
Catalog: DF3743
Description: Rabbit polyclonal antibody to SLC25A31
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 35 KD; 35kD(Calculated).
Uniprot: Q9H0C2
RRID: AB_2836107

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
SLC25A31 Antibody detects endogenous levels of total SLC25A31.
RRID:
AB_2836107
Cite Format: Affinity Biosciences Cat# DF3743, RRID:AB_2836107.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AAC4; Adenine nucleotide translocator 4; ADP; ADP,ATP carrier protein 4; ADP/ATP translocase 4; ADT4_HUMAN; ANT 4; ANT4; ATP carrier protein 4; SFEC; Slc25a31; Solute carrier family 25 member 31; Sperm flagellar energy carrier protein;

Immunogens

Immunogen:
Uniprot:

Q9H0C2(ADT4_HUMAN) >>Visit HPA database.

Gene(ID):
SLC25A31(83447)
Expression:
Q9H0C2 ADT4_HUMAN:

Expressed in brain, liver, sperm and testis.

Sequence:
MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFHIDIGGR

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H0C2 As Substrate

Site PTM Type Enzyme
S34 Phosphorylation
T36 Phosphorylation
S58 Phosphorylation
Y63 Phosphorylation
Y93 Phosphorylation
T96 Phosphorylation
K104 Acetylation
K104 Ubiquitination
K106 Acetylation
K106 Ubiquitination
S113 Phosphorylation
K117 Ubiquitination
K218 Acetylation
K219 Acetylation
Y261 Phosphorylation
T264 Phosphorylation

Research Backgrounds

Function:

Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility.

Subcellular Location:

Mitochondrion inner membrane>Multi-pass membrane protein. Cell projection>Cilium>Flagellum.
Note: In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in brain, liver, sperm and testis.

Family&Domains:

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Research Fields

· Cellular Processes > Cell growth and death > Necroptosis.   (View pathway)

· Cellular Processes > Cell growth and death > Cellular senescence.   (View pathway)

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

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