PGD Antibody - #DF3714

(2)  
Product: PGD Antibody
Catalog: DF3714
Description: Rabbit polyclonal antibody to PGD
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 40 KD; 53kD(Calculated).
Uniprot: P52209
RRID: AB_2836078

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(91%)
Clonality:
Polyclonal
Specificity:
PGD Antibody detects endogenous levels of total PGD.
RRID:
AB_2836078
Cite Format: Affinity Biosciences Cat# DF3714, RRID:AB_2836078.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

0610042A05Rik; 6 phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase; 6PGD; 6PGD_HUMAN; AU019875; C78335; decarboxylating; OTTMUSP00000011754; Pgd; Phosphogluconate dehydrogenase; RP23-249G3.4;

Immunogens

Immunogen:

A synthesized peptide derived from human PGD, corresponding to a region within C-terminal amino acids.

Uniprot:

P52209(6PGD_HUMAN) >>Visit HPA database.

Gene(ID):
PGD(5226)
Sequence:
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Zebrafish
100
Chicken
100
Rabbit
100
Xenopus
91
Pig
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P52209 As Substrate

Site PTM Type Enzyme
K38 Acetylation
K38 Ubiquitination
K48 Ubiquitination
K51 Ubiquitination
S57 Phosphorylation
K59 Acetylation
K59 Ubiquitination
K76 Acetylation
S104 Phosphorylation
Y106 Phosphorylation
K119 Ubiquitination
S126 Phosphorylation
S129 Phosphorylation
K147 Acetylation
K147 Ubiquitination
K154 Acetylation
K154 Ubiquitination
K163 Ubiquitination
T166 Phosphorylation
K184 Ubiquitination
K248 Acetylation
K248 Ubiquitination
K253 Ubiquitination
S257 Phosphorylation
K261 Ubiquitination
K265 Ubiquitination
K294 Acetylation
K294 Ubiquitination
K309 Acetylation
K309 Ubiquitination
K316 Acetylation
K316 Ubiquitination
K317 Ubiquitination
S318 Phosphorylation
R324 Methylation
K377 Ubiquitination
K460 Ubiquitination
T475 Phosphorylation
S479 Phosphorylation
S480 Phosphorylation
Y481 Phosphorylation

Research Backgrounds

Function:

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the 6-phosphogluconate dehydrogenase family.

Research Fields

· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.

· Metabolism > Metabolism of other amino acids > Glutathione metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Metabolism > Global and overview maps > Carbon metabolism.

Restrictive clause

 

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For Research Use Only.
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