Product: MRPL22 Antibody
Catalog: DF3665
Description: Rabbit polyclonal antibody to MRPL22
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 24 KD; 24kD(Calculated).
Uniprot: Q9NWU5
RRID: AB_2836037

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(92%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(85%)
Clonality:
Polyclonal
Specificity:
MRPL22 Antibody detects endogenous levels of total MRPL22.
RRID:
AB_2836037
Cite Format: Affinity Biosciences Cat# DF3665, RRID:AB_2836037.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

MRPL22; 39S ribosomal protein L22; 39S ribosomal protein L22 mitochondrial precursor; 39S ribosomal protein L25; 39S ribosomal protein L25, mitochondrial; E030011D16Rik; HSPC158; L22mt; L25mt; mitochondrial; mitochondrial ribosomal protein L22; MRP L22; MRP L25; MRP-L22; MRP-L25; Mrpl22; RM22_HUMAN; RPML25;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MAAAVLGQLGALWIHNLRSRGKLALGVLPQSYIHTSASLDISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGRGQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPPEPPKTAVAHAKEYIQQLRSRTIVHTL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Zebrafish
92
Chicken
85
Horse
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NWU5 As Substrate

Site PTM Type Enzyme
Y68 Phosphorylation
K86 Ubiquitination
K105 Ubiquitination
K112 Ubiquitination
R143 Methylation
Y165 Phosphorylation
K184 Ubiquitination
K191 Ubiquitination
Y193 Phosphorylation

Research Backgrounds

Subcellular Location:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.

Family&Domains:

Belongs to the universal ribosomal protein uL22 family.

Research Fields

· Genetic Information Processing > Translation > Ribosome.

Restrictive clause

 

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