SERC1 Antibody | Affinity Biosciences

WB
IHC
IF/ICC

1/6

Western blot analysis on HepG2 cell lysates using SERC1 Antibody,The lane on the left was treated with the antigen-specific peptide.

AF0374 at 1/100 staining mouse heart tissue by IHC-P.

AF0374 at 1/100 staining mouse brain tissue by IHC-P.

AF0374 at 1/100 staining rat heart tissue by IHC-P.

AF0374 at 1/100 staining rat muscle tissue by IHC-P.

AF0374 staining HepG2 cells by IF/ICC.

Product:	SERC1 Antibody
Catalog:	AF0374
Description:	Rabbit polyclonal antibody to SERC1
Application:	WB IHC IF/ICC
Reactivity:	Human, Mouse, Rat
Mol.Wt.:	48kDa; 50kD(Calculated).
Uniprot:	Q9NRX5
RRID:	AB_2833535

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

IHC 1:50-1:200, WB 1:500-1:3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Clonality:

Polyclonal

Specificity:

SERC1 Antibody detects endogenous levels of total SERC1.

RRID:

AB_2833535
Cite Format: Affinity Biosciences Cat# AF0374, RRID:AB_2833535.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

1500011D18Rik; AI315070; AIGP 2; KIAA1253; LRRGT00191; mKIAA1253; SERC1_HUMAN; SERINC1; Serine incorporator 1; TDE1L; TDE2; TMS 2; Tms2; Tumor differentially expressed 1 protein like; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2; UNQ396/PRO732;

Immunogens

Immunogen:

A synthesized peptide derived from human SERC1, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9NRX5(SERC1_HUMAN) >>Visit HPA database.

Gene(ID):

SERINC1(57515)

Description:

SERINC1 Enhances the incorporation of serine into phosphatidylserine and sphingolipids. Belongs to the TDE1 family. Interacts with SPTLC1.

Sequence:

Q9NRX5 SERC1_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD

PTMs - Q9NRX5 As Substrate

Q9NRX5

Site	PTM Type	Source
G2	Myristoylation	Uniprot
S31	Phosphorylation	Uniprot
S35	Phosphorylation	Uniprot
T36	Phosphorylation	Uniprot
T38	Phosphorylation	Uniprot
N298	N-Glycosylation	Uniprot
K343	Ubiquitination	Uniprot
T345	Phosphorylation	Uniprot
T347	Phosphorylation	Uniprot
S348	Phosphorylation	Uniprot
S351	Phosphorylation	Uniprot
T352	Phosphorylation	Uniprot
S361	Phosphorylation	Uniprot
S364	Phosphorylation	Uniprot
Y410	Phosphorylation	Uniprot
S413	Phosphorylation	Uniprot
S418	Phosphorylation	Uniprot
T421	Phosphorylation	Uniprot

Research Backgrounds

Q9NRX5_SERC1_HUMAN

Function:

Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

Subcellular Location:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Subunit Structure:

Interacts with SPTLC1.

Family&Domains:

Belongs to the TDE1 family.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

SERC1 Antibody - #AF0374