CADM4 Antibody - #DF3538
| Product: | CADM4 Antibody |
| Catalog: | DF3538 |
| Description: | Rabbit polyclonal antibody to CADM4 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 48 KD; 43kD(Calculated). |
| Uniprot: | Q8NFZ8 |
| RRID: | AB_2835911 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3538, RRID:AB_2835911.
Fold/Unfold
CADM 4; cadm4; CADM4_HUMAN; Cell adhesion molecule 4; IGSF4C; Immunoglobulin superfamily member 4C; Necl 4; NECL-4; NECL4; Nectin like 4; Nectin like protein 4; Nectin-like protein 4; synCAM4; TSLC1 like 2; TSLC1 like protein 2; TSLC1-like protein 2; TSLL2;
Immunogens
- Q8NFZ8 CADM4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLNGSDGHKRKEEFFI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8NFZ8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T63 | Phosphorylation | Uniprot | |
| T69 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| S223 | Phosphorylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| S377 | Phosphorylation | Uniprot | |
| K381 | Ubiquitination | Uniprot |
Research Backgrounds
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
N-glycosylated.
Membrane>Single-pass type I membrane protein.
Expressed in brain, prostate, brain, kidney and some other organs.
Monomer and homodimer.
Belongs to the nectin family.
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