CAPN11 Antibody - #DF3867
(3)
| Product: | CAPN11 Antibody |
| Catalog: | DF3867 |
| Description: | Rabbit polyclonal antibody to CAPN11 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Mol.Wt.: | 81 KD; 84kD(Calculated). |
| Uniprot: | Q9UMQ6 |
| RRID: | AB_2835905 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Polyclonal
Specificity:
CAPN11 Antibody detects endogenous levels of total CAPN11.
RRID:
AB_2835905
Cite Format: Affinity Biosciences Cat# DF3867, RRID:AB_2835905.
Cite Format: Affinity Biosciences Cat# DF3867, RRID:AB_2835905.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Calcium activated neutral proteinase 11; Calpain11; CAPN 11; CAPN11;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Expression:
Sequence:
- Q9UMQ6 CAN11_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLYSPGPSLPESAESLDGSQEDKPRGSCAEPTFTDTGMVAHINNSRLKAKGVGQHDNAQNFGNQSFEELRAACLRKGELFEDPLFPAEPSSLGFKDLGPNSKNVQNISWQRPKDIINNPLFIMDGISPTDICQGILGDCWLLAAIGSLTTCPKLLYRVVPRGQSFKKNYAGIFHFQIWQFGQWVNVVVDDRLPTKNDKLVFVHSTERSEFWSALLEKAYAKLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQRPPQNLLRLLRKAVERSSLMGCSIEVTSDSELESMTDKMLVRGHAYSVTGLQDVHYRGKMETLIRVRNPWGRIEWNGAWSDSAREWEEVASDIQMQLLHKTEDGEFWMSYQDFLNNFTLLEICNLTPDTLSGDYKSYWHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEGDDPEDDAEGNVVVCTCLVALMQKNWRHARQQGAQLQTIGFVLYAVPKEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVSSQLRLPPGEYIIIPSTFEPHRDADFLLRVFTEKHSESWELDEVNYAEQLQEEKVSEDDMDQDFLHLFKIVAGEGKEIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINLMDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVARYADDDLIIDFDSFISCFLRLKTMFTFFLTMDPKNTGHICLSLEQWLQMTMWG
PTMs - Q9UMQ6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T314 | Phosphorylation | Uniprot | |
| S404 | Phosphorylation | Uniprot | |
| Y493 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| S509 | Phosphorylation | Uniprot | |
| S510 | Phosphorylation | Uniprot | |
| K679 | Acetylation | Uniprot |
Research Backgrounds
Function:
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Subcellular Location:
Cytoplasmic vesicle>Secretory vesicle>Acrosome.
Tissue Specificity:
Highest expression in testis.
Subunit Structure:
Heterodimer of a large (catalytic) and a small (regulatory) subunit.
Family&Domains:
Belongs to the peptidase C2 family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.