SERC1 Antibody | Affinity Biosciences

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Western blot analysis of extracts from HepG2 cells, using SERC1 antibody.

Western blot analysis of extracts from HepG2 cells, using SERC1 Antibody.

Product:	SERC1 Antibody
Catalog:	DF3446
Description:	Rabbit polyclonal antibody to SERC1
Application:	WB IF/ICC
Reactivity:	Human, Mouse, Rat
Mol.Wt.:	48 KD; 50kD(Calculated).
Uniprot:	Q9NRX5
RRID:	AB_2835812

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Clonality:

Polyclonal

Specificity:

SERC1 Antibody detects endogenous levels of total SERC1.

RRID:

AB_2835812
Cite Format: Affinity Biosciences Cat# DF3446, RRID:AB_2835812.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

1500011D18Rik; AI315070; AIGP 2; KIAA1253; LRRGT00191; mKIAA1253; SERC1_HUMAN; SERINC1; Serine incorporator 1; TDE1L; TDE2; TMS 2; Tms2; Tumor differentially expressed 1 protein like; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2; UNQ396/PRO732;

Immunogens

Immunogen:

A synthesized peptide derived from human SERC1, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9NRX5(SERC1_HUMAN) >>Visit HPA database.

Gene(ID):

SERINC1(57515)

Sequence:

Q9NRX5 SERC1_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD

PTMs - Q9NRX5 As Substrate

Q9NRX5

Site	PTM Type	Source
G2	Myristoylation	Uniprot
S31	Phosphorylation	Uniprot
S35	Phosphorylation	Uniprot
T36	Phosphorylation	Uniprot
T38	Phosphorylation	Uniprot
N298	N-Glycosylation	Uniprot
K343	Ubiquitination	Uniprot
T345	Phosphorylation	Uniprot
T347	Phosphorylation	Uniprot
S348	Phosphorylation	Uniprot
S351	Phosphorylation	Uniprot
T352	Phosphorylation	Uniprot
S361	Phosphorylation	Uniprot
S364	Phosphorylation	Uniprot
Y410	Phosphorylation	Uniprot
S413	Phosphorylation	Uniprot
S418	Phosphorylation	Uniprot
T421	Phosphorylation	Uniprot

Research Backgrounds

Q9NRX5_SERC1_HUMAN

Function:

Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

Subcellular Location:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Subunit Structure:

Interacts with SPTLC1.

Family&Domains:

Belongs to the TDE1 family.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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SERC1 Antibody - #DF3446