Product: MOBKL2A/B Antibody
Catalog: DF3395
Description: Rabbit polyclonal antibody to MOBKL2A/B
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Mol.Wt.: 25 KD; 25kD(Calculated).
Uniprot: Q96BX8 | Q86TA1
RRID: AB_2835777

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
MOBKL2A/B Antibody detects endogenous levels of total MOBKL2A/B.
RRID:
AB_2835777
Cite Format: Affinity Biosciences Cat# DF3395, RRID:AB_2835777.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

MOB-LAK; Mob1 homolog 2A; MOBKL2A; MOL2A_HUMAN; Mps one binder kinase activator-like 2A; Protein Mob3A; Mob1 homolog 2b; MOB1 Mps One Binder kinase activator like 2B (yeast); MOB1 Mps One Binder kinase activator like 2B; MOB3B; MOBKL2B; MOL2B_HUMAN; monopolar spindle 1 binding MOB1 domain containing; Mps one binder kinase activator-like 2B; Protein Mob3B;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH

MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96BX8/Q86TA1 As Substrate

Site PTM Type Enzyme
T14 Phosphorylation
K20 Ubiquitination
T25 Phosphorylation
T77 Phosphorylation
K208 Ubiquitination
Site PTM Type Enzyme
S2 Phosphorylation
K7 Ubiquitination
T15 Phosphorylation
K21 Ubiquitination
T26 Phosphorylation
S38 Phosphorylation
K96 Sumoylation
K106 Ubiquitination
K109 Ubiquitination
T111 Phosphorylation
S114 Phosphorylation
K203 Ubiquitination
K209 Ubiquitination

Research Backgrounds

Function:

May regulate the activity of kinases.

Family&Domains:

Belongs to the MOB1/phocein family.

Function:

Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Family&Domains:

Belongs to the MOB1/phocein family.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.