HLX1 Antibody - #DF3279
| Product: | HLX1 Antibody |
| Catalog: | DF3279 |
| Description: | Rabbit polyclonal antibody to HLX1 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Rabbit, Dog, Chicken |
| Mol.Wt.: | 75 KD; 51kD(Calculated). |
| Uniprot: | Q14774 |
| RRID: | AB_2835647 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3279, RRID:AB_2835647.
Fold/Unfold
H2.0 like homeo box 1; H2.0 like homeobox 1; H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HB24; HLX; HLX_HUMAN; Homeobox protein HB24; Homeobox protein HLX1;
Immunogens
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
- Q14774 HLX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEPAQGALGCL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14774 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S152 | Phosphorylation | Uniprot | |
| T154 | Phosphorylation | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| T271 | Phosphorylation | Uniprot | |
| Y272 | Phosphorylation | Uniprot | |
| S277 | Phosphorylation | Uniprot | |
| S366 | Phosphorylation | Uniprot | |
| S400 | Phosphorylation | Uniprot | |
| T404 | Phosphorylation | Uniprot | |
| S477 | Phosphorylation | Uniprot |
Research Backgrounds
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
Nucleus.
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
Belongs to the H2.0 homeobox family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.