Parathyroid Hormone Recombinant Rabbit mAb - #BF4368

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Product: Parathyroid Hormone Recombinant Rabbit mAb
Catalog: BF4368
Description: Rabbit monoclonal antibody to Parathyroid Hormone
Application: WB IHC
Reactivity: Human
Mol.Wt.: 12kDa(Observed); 13kD(Calculated).
Uniprot: P01270

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MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit IgG
Application:
WB 1:1000-1:5000, IHC 1:200-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [ReFirm23818]
Specificity:
Parathyroid Hormone Recombinant Rabbit mAb detects endogenous levels of Parathyroid Hormone.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

hPTH; Parathormone; Parathyrin; Parathyroid hormone 1; Parathyroid hormone; Prepro PTH; Preproparathyroid hormone; PTH; PTH1; PTH1 receptor; PTH1R; PTHR; PTHR1; PTHY_HUMAN;

Immunogens

Immunogen:

A synthetic peptide from human Parathyroid Hormone

Uniprot:

P01270(PTHY_HUMAN) >>Visit HPA database.

Gene(ID):
PTH(5741)
Description:
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone,parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein,known as hyperparathyroidism,can result in hypercalcemia and kidney stones. On the other hand,defective processing of the encoded protein may lead to hypoparathyroidism,which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.
Sequence:
MIPAKDMAKVMIVMLAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVNVLTKAKSQ

Research Backgrounds

Function:

PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the parathyroid hormone family.

Restrictive clause

 

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For Research Use Only.
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