VEGF Receptor 2 Recombinant Rabbit mAb - #BF4150
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Product Info
Source:
Rabbit IgG
Application:
WB 1:1000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Mouse, Rat
Clonality:
Monoclonal [ReFirm23597]
Specificity:
VEGF Receptor 2 Recombinant Rabbit mAb detects endogenous levels of VEGF Receptor 2.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
orv,Flk1,Ly73,Flk-1,Krd-1,VEGFR2,VEGFR-2,sVEGFR-2,6130401C07
Immunogens
Immunogen:
A synthetic peptide from mouse VEGF Receptor 2
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA,VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis,vascular development,vascular permeability,and embryonic hematopoiesis. Promotes proliferation,survival,migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain,such as isoform 2,may function as decoy receptors for VEGFA,VEGFC and,or VEGFD. Isoform 2 plays an important role as a negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and,or VEGFC and by preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers.
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