Adrenergic Receptor alpha -2C Antibody - #DF3108
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| Product: | Adrenergic Receptor alpha -2C Antibody |
| Catalog: | DF3108 |
| Description: | Rabbit polyclonal antibody to Adrenergic Receptor alpha -2C |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Horse, Dog, Chicken, Xenopus |
| Mol.Wt.: | 70 KD; 50kD(Calculated). |
| Uniprot: | P18825 |
| RRID: | AB_2835485 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3108, RRID:AB_2835485.
Fold/Unfold
Adra 2c; ADRA2C; ADRA2L2; ADRA2RL2; ADRARL2; Adrenergic alpha 2C receptor; Adrenoceptor alpha 2C; Alpha 2C adrenergic receptor; Alpha 2C adrenergic receptor subtype C4; Alpha 2C adrenoceptor; Alpha 2C adrenoreceptor; Alpha 2CAR; Alpha-2-adrenergic receptor, renal type; alpha2 AR C4; alpha2 C4; alpha2C; ALPHA2CAR; alpha2cii-adrenergic receptor; Subtype alpha2 C4;
Immunogens
- P18825 ADA2C_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P18825 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S338 | Phosphorylation | Uniprot | |
| S352 | Phosphorylation | Uniprot | |
| S358 | Phosphorylation | Uniprot |
Research Backgrounds
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Cell membrane>Multi-pass membrane protein.
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
Research Fields
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
References
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