HNF1 beta Antibody - #AF4101
| Product: | HNF1 beta Antibody |
| Catalog: | AF4101 |
| Description: | Rabbit polyclonal antibody to HNF1 beta |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 45,58,61kd; 61kD(Calculated). |
| Uniprot: | P35680 |
| RRID: | AB_2835368 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF4101, RRID:AB_2835368.
Fold/Unfold
FJHN; Hepatocyte nuclear factor 1 beta; Hepatocyte nuclear factor 1-beta; HNF 1B; HNF 2; HNF-1-beta; HNF-1B; HNF1 beta; HNF1 homeobox B; HNF1B; HNF1B_HUMAN; HNF1beta; HNF2; Homeoprotein LF B3; Homeoprotein LFB3; HPC11; LF B3; LFB3; MODY 5; MODY5; TCF 2; TCF 2 protein; TCF-2; TCF2; TCF2 protein; Transcription factor 2; Transcription factor 2 hepatic; Variant hepatic nuclear factor 1; Variant hepatic nuclear factor; VHNF 1; vHNF1;
Immunogens
- P35680 HNF1B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P35680 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S49 | Phosphorylation | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| S80 | Phosphorylation | Uniprot | |
| T88 | Phosphorylation | Uniprot | |
| S279 | Phosphorylation | Uniprot | |
| S281 | Phosphorylation | Uniprot | |
| S288 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S538 | Phosphorylation | Uniprot |
Research Backgrounds
Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
Nucleus.
Binds DNA as a dimer. Can form homodimer or heterodimer with HNF1-alpha.
Belongs to the HNF1 homeobox family.
Research Fields
· Human Diseases > Endocrine and metabolic diseases > Maturity onset diabetes of the young.
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