Product: PRPS1L1 Antibody
Catalog: DF16106
Description: Rabbit polyclonal antibody to PRPS1L1
Application: WB IHC IF/ICC
Reactivity: Human
Mol.Wt.: 35kD(Calculated).
Uniprot: P21108

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
PRPS1L1 Antibody detects endogenous levels of PRPS1L1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

phosphoribosyl pyrophosphate synthase 1 like 1; phosphoribosyl pyrophosphate synthase III; Phosphoribosyl pyrophosphate synthetase 1 like 1; Phosphoribosyl pyrophosphate synthetase III; Phosphoribosylpyrophosphate synthetase 1 like 1; Phosphoribosylpyrophosphate synthetase 3; phosphoribosylpyrophosphate synthetase subunit III; PRPS 1; PRPS 3; PRPS1; PRPS1 like 1; PRPS3; PRPSL; PRS III; PRSIII; ribose phosphate diphosphokinase catalytic chain III; Ribose phosphate pyrophosphokinase 3; Ribose phosphate pyrophosphokinase; Ribose phosphate pyrophosphokinase III;

Immunogens

Immunogen:

A synthesized peptide derived from human PRPS1L1.

Uniprot:
Gene(ID):
Expression:
Sequence:
MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGEINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAGADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTSIADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAGATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAIRRTHNGESVSYLFSHVPL

Research Backgrounds

Function:

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

Tissue Specificity:

Testis.

Subunit Structure:

Homodimer. The active form is probably a hexamer composed of 3 homodimers (By similarity).

Family&Domains:

Belongs to the ribose-phosphate pyrophosphokinase family.

Research Fields

· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Metabolism > Global and overview maps > Carbon metabolism.

· Metabolism > Global and overview maps > Biosynthesis of amino acids.

Restrictive clause

 

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