STOML1 Antibody - #DF16103

(3)  
Product: STOML1 Antibody
Catalog: DF16103
Description: Rabbit polyclonal antibody to STOML1
Application: IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 50kD; 43kD(Calculated).
Uniprot: Q9UBI4

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
STOML1 Antibody detects endogenous levels of STOML1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EPB72 like 1; hUNC 24; SLP 1; SLP1; Stomatin (EBP72) like 1; Stomatin related protein; STORP; UNC24;

Immunogens

Immunogen:

A synthesized peptide derived from human STOML1.

Uniprot:

Q9UBI4(STML1_HUMAN) >>Visit HPA database.

Gene(ID):
STOML1(9399)
Expression:
Q9UBI4 STML1_HUMAN:

Ubiquitously expressed at low levels. Expression is highest in brain.

Sequence:
MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPERGGVGTGADVPQSWPSCLCHGLISFLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQQLALHFLGGSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTALQPFLSEALVSQVGACYQFNVVLPSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLRALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRALK

Research Backgrounds

Function:

May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation.

Subcellular Location:

Membrane>Single-pass type III membrane protein. Late endosome membrane. Membrane raft. Cell membrane>Single-pass type III membrane protein. Cytoplasmic vesicle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitously expressed at low levels. Expression is highest in brain.

Subunit Structure:

Interacts with STOM; may redistribute STOM from the plasma membrane to late endosomes. Interacts with FBXW7 isoform 3 and CDK2.

Family&Domains:

Belongs to the band 7/mec-2 family.

Restrictive clause

 

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