PANK1 Antibody | Affinity Biosciences

IHC
IF/ICC

1/2

DF16096 at 1/100 staining mouse liver tissue by IHC-P.

Product:	PANK1 Antibody
Catalog:	DF16096
Description:	Rabbit polyclonal antibody to PANK1
Application:	IHC IF/ICC
Reactivity:	Human, Mouse
Mol.Wt.:	64kD(Calculated).
Uniprot:	Q8TE04

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse

Clonality:

Polyclonal

Specificity:

PANK1 Antibody detects endogenous levels of PANK1.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

coaA; hPanK; hPanK1; PANK; PANK1; PANK1_HUMAN; PANK1a; PANK1b; PanK1beta; Pantothenate kinase 1; Pantothenate kinase; Pantothenic acid kinase 1;

Immunogens

Immunogen:

A synthesized peptide derived from human PANK1.

Uniprot:

Q8TE04(PANK1_HUMAN) >>Visit HPA database.

Gene(ID):

PANK1(53354)

Expression:

Q8TE04 PANK1_HUMAN:

Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.

Sequence:

Q8TE04 PANK1_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MLKLVGGGGGQDWACSVAGTSLGGEEAAFEVARPGDQGKAGGGSPGWGCAGIPDSAPGAGVLQAGAVGPARGGQGAEEVGESAGGGEERRVRHPQAPALRLLNRKPQGGSGEIKTPENDLQRGRLSRGPRTAPPAPGMGDRSGQQERSVPHSPGAPVGTSAAAVNGLLHNGFHPPPVQPPHVCSRGPVGGSDAAPQRLPLLPELQPQPLLPQHDSPAKKCRLRRRMDSGRKNRPPFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPSCAMHRFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRDSISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDDK

Research Backgrounds

Q8TE04_PANK1_HUMAN

Function:

Plays a role in the physiological regulation of the intracellular CoA concentration.

Subcellular Location:

Cytoplasm.

Tissue Specificity:

Subunit Structure:

Homodimer.

Family&Domains:

The N-terminal extension, present in isoform 1 may be the regulatory domain.

Belongs to the type II pantothenate kinase family.

Research Fields

· Metabolism > Metabolism of cofactors and vitamins > Pantothenate and CoA biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

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For Research Use Only.
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PANK1 Antibody - #DF16096