DECR1 Antibody - #DF16078

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Product: DECR1 Antibody
Catalog: DF16078
Description: Rabbit polyclonal antibody to DECR1
Application: WB
Reactivity: Human, Mouse, Rat
Mol.Wt.: 36kD(Calculated).
Uniprot: Q16698

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
DECR1 Antibody detects endogenous levels of DECR1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1200012F07Rik; 2; 2,4 dienoyl CoA reductase [NADPH]; 2,4 dienoyl CoA reductase 1; 2,4 dienoyl CoA reductase mitochondrial; 2,4-dienoyl-CoA reductase, mitochondrial; 4 enoyl CoA reductase; 4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; DECR 1; DECR; DECR_HUMAN; DECR1; Nadph; OTTMUSP00000004962; RP23-338J24.3; SDR18C1; Short chain dehydrogenase/reductase family 18C member 1;

Immunogens

Immunogen:

A synthesized peptide derived from human DECR1.

Uniprot:

Q16698(DECR_HUMAN) >>Visit HPA database.

Gene(ID):
DECR1(1666)
Expression:
Q16698 DECR_HUMAN:

Heart = liver = pancreas > kidney >> skeletal muscle = lung.

Sequence:
MKLPARVFFTLGSRLPCGLAPRRFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKEQWDTIEELIRKTKGS

Research Backgrounds

Function:

Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.

Subcellular Location:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Heart = liver = pancreas > kidney >> skeletal muscle = lung.

Subunit Structure:

Homotetramer.

Family&Domains:

Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.

Restrictive clause

 

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