Product: ST3GAL4 Antibody
Catalog: DF15963
Description: Rabbit polyclonal antibody to ST3GAL4
Application: IHC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 35-40kD; 38kD(Calculated).
Uniprot: Q11206

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
ST3GAL4 Antibody detects endogenous levels of ST3GAL4.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Alpha 2 3 sialyltransferase IV; Alpha 2 3 ST; Alpha 3 N acetylneuraminyltransferase; Beta galactoside alpha 2 3 sialyltransferase; CGS23; CMP N acetylneuraminate beta galactosamide alpha 2 3 sialyltransferase; FLJ11867; FLJ46764; Gal NAc6S; NANTA3; SAT 3; SAT3; Sialyltransferase 4C (beta galactosidase alpha 2 3 sialytransferase); Sialyltransferase 4C (beta galactoside alpha 2 3 sialytransferase); SIAT4; SIAT4 C; SIAT4C; ST 4; ST3 beta galactoside alpha 2 3 sialyltransferase 4; ST3Gal III; ST3GAL4; ST3GalIV; ST4; STZ;

Immunogens

Immunogen:

A synthesized peptide derived from human ST3GAL4.

Uniprot:
Gene(ID):
Expression:
Q11206 SIA4C_HUMAN:

Highly expressed in adult placenta, ovary and testes.

Sequence:
MVSKSRWKLLAMLALVLVVMVWYSISREDRYIELFYFPIPEKKEPCLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITSSSIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSMAGSGHNVSQEALAIKRMLEMGAIKNLTSF

Research Backgrounds

Function:

Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, and NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant.

PTMs:

The soluble form derives from the membrane form by proteolytic processing.

Subcellular Location:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein. Secreted.
Note: Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in adult placenta, ovary and testes.

Family&Domains:

Belongs to the glycosyltransferase 29 family.

Research Fields

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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