ADSSL1 Antibody - #DF15920

(2)  
Product: ADSSL1 Antibody
Catalog: DF15920
Description: Rabbit polyclonal antibody to ADSSL1
Application: WB IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 50kD(Calculated).
Uniprot: Q8N142

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
ADSSL1 Antibody detects endogenous levels of ADSSL1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Adenylosuccinate synthase like 1; Adenylosuccinate synthetase; Adenylosuccinate synthetase isozyme 1; AdSS 1; ADSS1; ADSSL1; AMPSase 1; basic isozyme; IMP aspartate ligase 1; IMP--aspartate ligase 1; M-type adenylosuccinate synthetase; muscle isozyme; PURA1_HUMAN;

Immunogens

Immunogen:

A synthesized peptide derived from human ADSSL1.

Uniprot:

Q8N142(PURA1_HUMAN) >>Visit HPA database.

Gene(ID):
ADSSL1(122622)
Expression:
Q8N142 PURA1_HUMAN:

Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors.

Sequence:
MSGTRASNDRPPGAGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF

Research Backgrounds

Function:

Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the adenylosuccinate synthetase family.

Research Fields

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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