ELAC1 Antibody - #DF15862

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Product: ELAC1 Antibody
Catalog: DF15862
Description: Rabbit polyclonal antibody to ELAC1
Application: WB
Reactivity: Human, Mouse
Mol.Wt.: 40-50kD; 40kD(Calculated).
Uniprot: Q9H777

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
ELAC1 Antibody detects endogenous levels of ELAC1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

D29; Deleted in Ma29; ELAC 1; ElaC homolog 1 (E. coli); ElaC homolog 1; ElaC homolog protein 1; ELAC1; Ribonuclease Z 1; RNase Z 1; RNZ1_HUMAN; tRNA 3 endonuclease 1; tRNA 3' processing endoribonuclease; tRNA Z (short form); tRNA Z; tRNase Z 1; tRNase ZS; Zinc phosphodiesterase ELAC protein 1;

Immunogens

Immunogen:

A synthesized peptide derived from human ELAC1.

Uniprot:

Q9H777(RNZ1_HUMAN) >>Visit HPA database.

Gene(ID):
ELAC1(55520)
Expression:
Q9H777 RNZ1_HUMAN:

Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Sequence:
MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSMVSKQPIEIYGPVGLRDFIWRTMELSHTELVFHYVVHELVPTADQCPAEELKEFAHVNRADSPPKEEQGRTILLDSEENSYLLFDDEQFVVKAFRLFHRIPSFGFSVVEKKRPGKLNAQKLKDLGVPPGPAYGKLKNGISVVLENGVTISPQDVLKKPIVGRKICILGDCSGVVGDGGVKLCFEADLLIHEATLDDAQMDKAKEHGHSTPQMAATFAKLCRAKRLVLTHFSQRYKPVALAREGETDGIAELKKQAESVLDLQEVTLAEDFMVISIPIKK

Research Backgrounds

Function:

Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

Subcellular Location:

Cytoplasm>Cytosol. Nucleus.
Note: Mainly cytosolic.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the RNase Z family.

Research Fields

· Genetic Information Processing > Translation > RNA transport.

Restrictive clause

 

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