TMEFF1 Antibody - #DF15812

Product: TMEFF1 Antibody
Catalog: DF15812
Description: Rabbit polyclonal antibody to TMEFF1
Application: ELISA(peptide)
Reactivity: Human, Mouse, Rat
Mol.Wt.: 41kD(Calculated).
Uniprot: Q8IYR6

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
TMEFF1 Antibody detects endogenous levels of TMEFF1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C9orf2; C9orf3 TMEFF1; C9orf30 TMEFF1; C9orf30 TMEFF1 fusion protein; Cancer/testis antigen family 120 member 1; CT120.1; H 7365; H7365; MSANTD3-TMEFF1 readthrough; TEFF 1; TEFF1; TEFF1_HUMAN; TMEFF 1; TMEFF1; Tomoregulin-1; Tomoregulin-1 precursor; TR 1; TR-1; TR1; Transmembrane protein with EGF like and two follistatin like domains 1; Transmembrane protein with EGF-like and one follistatin-like domain;

Immunogens

Immunogen:

A synthesized peptide derived from human TMEFF1.

Uniprot:

Q8IYR6(TEFF1_HUMAN) >>Visit HPA database.

Gene(ID):
TMEFF1(100526694)
Expression:
Q8IYR6 TEFF1_HUMAN:

Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.

Sequence:
MGAAAAEAPLRLPAAPPLAFCCYTSVLLLFAFSLPGSRASNQPPGGGGGSGGDCPGGKGKSINCSELNVRESDVRVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKEITVIARGPCYSDNGSGSGEGEEEGSGAEVHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV

Research Backgrounds

Function:

May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.

Subcellular Location:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.

Subunit Structure:

May interact with ST14.

Family&Domains:

Belongs to the tomoregulin family.

Restrictive clause

 

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