Product: UCK1 Antibody
Catalog: DF15591
Description: Rabbit polyclonal antibody to UCK1
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 31kD(Calculated).
Uniprot: Q9HA47

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
UCK1 Antibody detects endogenous levels of UCK1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cytidine monophosphate kinase; Cytidine monophosphokinase 1; Cytidylate kinase; Deoxycytidylate kinase; FLJ12255; OTTHUMP00000022400; OTTHUMP00000022401; OTTHUMP00000022403; OTTHUMP00000022404; RP11-334J6.5; UCK 1; uck1; UCK1_HUMAN; UMP-CMP kinase; Uridine monophosphokinase 1; Uridine-cytidine kinase 1; Uridine/cytidine kinase 1; URK1;

Immunogens

Immunogen:

A synthesized peptide derived from human UCK1.

Uniprot:
Gene(ID):
Expression:
Q9HA47 UCK1_HUMAN:

Ubiquitous.

Sequence:
MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Research Backgrounds

Function:

Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.

Tissue Specificity:

Ubiquitous.

Family&Domains:

Belongs to the uridine kinase family.

Research Fields

· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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